H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH | CAS No. 165893-48-1

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH

Basic Information

CAS Number

165893-48-1

Molecular Formula

C42H86N28O8

Molecular Weight

1111.3 g/mol

AD

Basic Physical Properties

C(CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)O)N)CN=C(N)N

InChI

InChI=1S/C42H86N28O8/c43-22(8-1-15-58-36(44)45)29(71)65-23(9-2-16-59-37(46)47)30(72)66-24(10-3-17-60-38(48)49)31(73)67-25(11-4-18-61-39(50)51)32(74)68-26(12-5-19-62-40(52)53)33(75)69-27(13-6-20-63-41(54)55)34(76)70-28(35(77)78)14-7-21-64-42(56)57/h22-28H,1-21,43H2,(H,65,71)(H,66,72)(H,67,73)(H,68,74)(H,69,75)(H,70,76)(H,77,78)(H4,44,45,58)(H4,46,47,59)(H4,48,49,60)(H4,50,51,61)(H4,52,53,62)(H4,54,55,63)(H4,56,57,64)/t22-,23-,24-,25-,26-,27-,28-/m0/s1

InChIKey

YCEORMDTHWMXDU-RMIXPHLWSA-N

LogP

-10.317699999999933

Topological Polar Surface Area

688.7199999999999 Ų

Hydrogen Bond Donor/Acceptor

37 / 36

Complexity

2110

Synonyms & References

English

  • 165893-48-1
  • H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
  • CHEMBL4081135
  • L-Arginine heptamer
  • Hepta-L-arginine
  • L-Arginine,L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-
  • ARG-ARG-ARG-ARG-ARG-ARG-ARG
  • Heptaarginine
  • H(-Arg)7-OH, Heptaarginine

MDL Number

MFCD06657936

FAQ

What are the physical and chemical properties of H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1)?

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1) is a polypeptide with a molecular weight of approximately 2400 Da. It is highly soluble in water and forms a crystalline solid at room temperature. Chemically, it is stable under neutral and slightly acidic conditions but hydrolyzes under basic conditions. It exhibits low reactivity with most common functional groups and is susceptible to enzymatic degradation.

How is H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1) typically synthesized?

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1) is typically synthesized via solid-phase peptide synthesis (SPPS) using a commercially available Fmoc-based protected amino acid sequence. The synthesis involves stepwise coupling of protected arginine residues, followed by deprotection and cleavage from the resin to yield the final product. The yield is typically around 70-85%, with high purity achieved through HPLC purification.

What industries use H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1)?

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1) finds applications in the pharmaceutical industry for research purposes, such as in drug discovery and development. It is also used in the biotechnology sector for protein engineering and in the research of peptide-based sensors and semiconductors.

What precautions should be taken when handling H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1)?

When handling H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH (CAS: 165893-48-1), it is recommended to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of aerosols. Spills should be managed carefully, and the area should be decontaminated. For detailed safety information, consult the Material Safety Data Sheet (MSDS/SDS).

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