Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

Basic Information

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CAS Number

165800-03-3

Molecular Formula

C16H20FN3O4

Molecular Weight

337.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

177-183°C

Boiling Point

585.5°C at 760 mmHg

Density

1.302

Flash Point

307.9 oC

Solubility

DMSO: >20mg/mL

Refractive Index

1.553

Specific Rotation

-9.0° - -15.0° (c=1, CHCl3)

SMILES

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CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F

InChI

InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

InChIKey

TYZROVQLWOKYKF-ZDUSSCGKSA-N

LogP

0.9

Topological Polar Surface Area

71.11 Å²

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

472

Safety Information

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GHS Hazard Pictograms

H372

Hazard Statement

H372 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Synonyms & References

English

SR-01000759376-5
Linezolid, >=98% (HPLC)
LINEZOLID IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
N-[[(5S)-3-(3-fluoranyl-4-morpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide
N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
NDA 21-131 Zyvox for injection (linezolid injection)
(S)-N-((3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
Zivoxid
PNU 100766
LINEZOLID (MART.)
MLS001424075
NDA 21-130 Zyvox (linezolid tablets)
A810662
LINEZOLID [USAN]
LINEZOLID [USP MONOGRAPH]
PNU-100766
NDA 21-132 Zyvox oral suspension (linzolid oral suspension)
HY-10394
BIDD:GT0404
(S)-N-[ [3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-oxazolidin-5-yl]methyl]-acetamide
Linezolid (JAN/USAN/INN)
N-(((5S)-3-(3-fluoro-4-(morpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamide
UNII-ISQ9I6J12J
N-((3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
NS00008464
CAS-165800-03-3
N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
HMS3260C14
N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide(linezolid)
Linezolid [USAN:INN:BAN]

MDL Number

MFCD21604223

Customs Code

2934999090

FAQ

What is Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS: 165800-03-3)?

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS: 165800-03-3) is a synthetic organic compound characterized by its complex structure, which includes an acetamide group attached to an oxazolidinyl ring. It is a white to off-white solid with a molecular formula of C16H22FNO4 and is commonly used in pharmaceutical research for its potential biological activity.

What are the main uses of Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS: 165800-03-3)?

This compound is primarily used in pharmaceutical research as a potential drug candidate, particularly in the development of antiviral and anti-inflammatory agents. It may also find applications in organic synthesis and as an intermediate in the production of various medicinal compounds.

Is Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS: 165800-03-3) safe?

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS: 165800-03-3) is generally considered safe when handled properly. However, as with many organic compounds, it may cause skin or eye irritation. It is recommended to use protective gloves, goggles, and ensure proper ventilation when working with this substance. Safety data sheets should be consulted for detailed handling guidelines.

How should Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS: 165800-03-3) be stored?

This compound should be stored in a cool, dry, and well-ventilated area, away from direct light. It is best kept in a sealed container to prevent moisture absorption. Storage conditions should maintain a temperature below 25°C and humidity levels below 60% to ensure stability and prolong shelf life.