Fmoc-D-Trp(Boc)-OH

Basic Information

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CAS Number

163619-04-3

Molecular Formula

C31H30N2O6

Molecular Weight

526.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

112-119°C

Refractive Index

1.632

Specific Rotation

+21.5° (c=1 in DMF)

SMILES

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CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CC(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

InChI

InChI=1S/C31H30N2O6/c1-31(2,3)39-30(37)33-17-19(20-10-8-9-15-27(20)33)16-26(28(34)35)32-29(36)38-18-25-23-13-6-4-11-21(23)22-12-5-7-14-24(22)25/h4-15,17,25-26H,16,18H2,1-3H3,(H,32,36)(H,34,35)/t26-/m1/s1

InChIKey

ADOHASQZJSJZBT-AREMUKBSSA-N

LogP

5.958900000000005

Topological Polar Surface Area

106.86 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Complexity

880

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(2R)-3-(1-tert-butoxycarbonylindol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
HY-79129
A-Fmoc-N(in)-Boc-D-tryptophan
(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid
(2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
EN300-95048
M03375
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
PD171436
N
SCHEMBL5969202
DTXSID60583788
CS-0011045
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-in-t-butyl-oxycarbonyl-D-tryptophan
1-(tert-Butoxycarbonyl)-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-D-tryptophan
1-Boc-N-Fmoc-D-tryptophan
Nalpha-Fmoc-N(in)-Boc-D-tryptophan
D-Tryptophan, 1-[(1,1-diMethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-
J-010069
1-Boc-Fmoc-D-tryptophan
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-in-t-butyloxycarbonyl-D-tryptophan
AC-8602
Na-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1-(tert-butoxycarbonyl)-D-tryptophan
Nalpha-Fmoc-N<sub.(in)-Boc-D-tryptophan
MFCD00153367
I10291
A810493
AKOS015907833
Fmoc-D-Trp(Boc)-OH, >=95.0% (HPLC)
(2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-3-indolyl]propanoic acid
Fmoc-D-Trp(Boc)-OH

MDL Number

MFCD00153367

Customs Code

29339900

FAQ

What is Fmoc-D-Trp(Boc)-OH (CAS: 163619-04-3)?

Fmoc-D-Trp(Boc)-OH is a protected amino acid derivative used in solid-phase peptide synthesis. It has the chemical formula C27H38N3O5 and is characterized by its ability to form stable bonds in the synthesis of peptides.

What are the main uses of Fmoc-D-Trp(Boc)-OH (CAS: 163619-04-3)?

Fmoc-D-Trp(Boc)-OH is primarily used in the chemical synthesis of peptides for pharmaceutical and research applications. It serves as a key building block in solid-phase peptide synthesis, facilitating the assembly of complex peptide sequences.

Is Fmoc-D-Trp(Boc)-OH (CAS: 163619-04-3) safe?

Fmoc-D-Trp(Boc)-OH is generally safe under proper handling conditions. However, it is important to follow safety guidelines, including wearing appropriate personal protective equipment (PPE) such as gloves and goggles. It is not considered toxic, but ingestion or exposure to the eyes should be avoided.

How should Fmoc-D-Trp(Boc)-OH (CAS: 163619-04-3) be stored?

Fmoc-D-Trp(Boc)-OH should be stored in a cool, dry place away from direct sunlight. It should be kept in a tightly sealed container to prevent moisture absorption. The recommended storage temperature is 2-8°C to ensure optimal stability and prevent degradation.