4'-Deoxy-20',20'-difluoro-8'-n | CAS No. 162652-95-1

4'-Deoxy-20',20'-difluoro-8'-n

Basic Information

CAS Number

162652-95-1

Molecular Formula

C45H54F2N4O8

Molecular Weight

816.9 g/mol

AD

Basic Physical Properties

CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=CC(=C(C=C45)C6(CC7CC(CN(C7)CC8=C6NC9=CC=CC=C89)C(C)(F)F)C(=O)OC)OC)C

InChI

InChI=1S/C45H54F2N4O8/c1-8-42-14-11-16-51-17-15-43(36(42)51)30-19-31(34(56-5)20-33(30)49(4)37(43)45(55,40(54)58-7)38(42)59-25(2)52)44(39(53)57-6)21-26-18-27(41(3,46)47)23-50(22-26)24-29-28-12-9-10-13-32(28)48-35(29)44/h9-14,19-20,26-27,36-38,48,55H,8,15-18,21-24H2,1-7H3/t26-,27-,36+,37-,38-,42-,43-,44+,45+/m1/s1

InChIKey

NMDYYWFGPIMTKO-HBVLKOHWSA-N

LogP

5.01950

Complexity

1720

Synonyms & References

English

  • vinfluninum
  • 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine
  • NMDYYWFGPIMTKO-KLCPSUAYSA-N
  • VINFLUNINE [WHO-DD]
  • L-0070
  • DTXSID30936722
  • UNII-5BF646324K
  • AKOS040759183
  • DB11641
  • vinflunina
  • VINFLUNINE [EMA EPAR]
  • Vinflunine [INN:BAN]
  • Vinflunine [INN]
  • CHEMBL2110725
  • 4'-Deoxy-20',20'-difluoro-C'-norvincaleukoblastine
  • 4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine
  • methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-4-[(12S,14S,16R)-16-(1,1-difluoroethyl)-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3(11),4(9),5,7-tetraen-12-yl]-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
  • VINFLUNINE [MI]
  • 162652-95-1
  • Vinflunine
  • VINFLUNINE [MART.]
  • HY-B0628
  • 20',20'-difluoro-3',4'-dihydrovinorelbine
  • EN300-33343034
  • CHEBI:90241
  • methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-4-[(12S,14S,16R)-16-(1,1-difluoroethyl)-12-methoxycarbonyl-1,10-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
  • Javlor
  • C'-Norvincaleukoblastine, 4'-deoxy-20',20'-difluoro-
  • 4'-DEOXY-20',20'-DIFLUORO-8'-NORVINCALEUCOBLASTINE
  • 5BF646324K
  • methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(12S,14S,16R)-16-(1,1-difluoroethyl)-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0(3,11).0(4,9)]octadeca-3(11),4,6,8-tetraen-12-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate

MDL Number

MFCD00938122

FAQ

What regulatory guidelines apply to 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1)?

4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1) must comply with the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations, and FDA/EPA guidelines for chemical products. Specific requirements include proper labeling with hazard statements, precautionary measures, and storage instructions. Compliance with local and regional regulations is also necessary.

Are there alternatives to 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1) in synthesis?

Alternatives to 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1) in synthesis include other fluorinated compounds and analogs with similar functional groups. Common substitutes include 20',20'-difluoro-8'-n and 4'-deoxy-20'-fluoro-8'-n. These alternatives may offer similar properties but with different reactivity and solubility characteristics.

What is the market or research trend for 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1)?

The market for 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1) is driven by its applications in pharmaceutical research, particularly in antiviral drug development. Recent research trends highlight its use in designing novel antiviral agents, with a focus on enhancing its antiviral efficacy and reducing side effects. Market demand is expected to grow with advancements in antiviral therapy.

How should waste containing 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1) be handled?

Waste containing 4'-Deoxy-20',20'-difluoro-8'-n (CAS: 162652-95-1) should be collected in appropriate containers and stored in a secure, well-ventilated area. Incineration or professional waste disposal services should be utilized to ensure environmental safety. Follow local hazardous waste disposal regulations and ensure that waste handlers are properly trained to handle and dispose of this compound safely and effectively.

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