(4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one

Basic Information

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CAS Number

16251-45-9

Molecular Formula

C10H11NO2

Molecular Weight

177.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

121-123 °C

Boiling Point

395.8°C at 760 mmHg

Flash Point

193.2℃

Refractive Index

1.5168 (estimate)

SMILES

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CC1C(OC(=O)N1)C2=CC=CC=C2

InChI

InChI=1S/C10H11NO2/c1-7-9(13-10(12)11-7)8-5-3-2-4-6-8/h2-7,9H,1H3,(H,11,12)/t7-,9-/m0/s1

InChIKey

PPIBJOQGAJBQDF-CBAPKCEASA-N

LogP

1.856

Topological Polar Surface Area

38.33 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

199

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H412 Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

rac-cis-4-methyl-5-phenyl-2-oxazolidinone
2-Oxazolidinone, 4-methyl-5-phenyl-, (4S,5R)-(-)-
(4S,5r)-4-methyl-5-phenyl-2-oxazolidinone
2-Oxazolidinone, 4-methyl-5-phenyl-, (4R,5S)-rel-
(R)-4-methyl-(S)-5-phenyl-oxazolidin-2-one
2-Oxazolidinone,4-methyl-5-phenyl-,(4S,5R)-
UNII-4KSX5DI61K
28044-22-6
AC-33543
Rel-(4S,5R)-4-methyl-5-phenyloxazolidin-2-one
PPIBJOQGAJBQDF-CBAPKCEASA-N
A882837
2-Oxazolidinone, 4-methyl-5-phenyl-, (4S,5R)-
(4S,5R)-4-methyl-5-phenyl-1,3-oxazolidin-2-one
(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one
(4S,5R)-(-)-4-Methyl-5-phenyl-2-oxazolidinone
4-Methyl-5-phenyl-2-oxazolidinone, cis-
UNII-PZO2G7843G
PS-3385
(4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one
(4S,5R)-(-)-4-Methyl-5-phenyl-2-oxazolidinone, 99%
PZO2G7843G
DTXSID10936705
cis-4-Methyl-5-phenyloxazolidin-2-one
4-Methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-ol
SCHEMBL4687
J-009944
16251-45-9
DTXSID40864668
4-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)-
4KSX5DI61K

MDL Number

MFCD00066226

FAQ

What is (4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one (CAS: 16251-45-9)?

(4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one is an organic compound with the CAS number 16251-45-9. It is a cyclic ketone with a distinct structure featuring an oxazolidinone ring. This compound is characterized by its chemical formula C10H11NO2 and is known for its structural rigidity and functional diversity.

What are the main uses of (4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one (CAS: 16251-45-9)?

(4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one is primarily used in pharmaceuticals and research. It serves as a key intermediate in the synthesis of various medicinal compounds, particularly anti-infective agents and anti-inflammatory drugs. Additionally, it finds applications in the development of new chemical entities and as a reagent in organic synthesis.

Is (4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one (CAS: 16251-45-9) safe?

(4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one is considered safe for laboratory use when proper precautions are taken. However, it is important to handle this compound with care due to its potential for skin irritation. Protective measures include wearing gloves and goggles, and ensuring adequate ventilation. Storage should be secured and away from sources of heat or ignition.

How should (4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one (CAS: 16251-45-9) be stored?

(4S,5R)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one should be stored in a cool, dark place, ideally at temperatures below 25°C and with a relative humidity below 50%. It should be kept in a tightly sealed container to prevent degradation and exposure to light. Avoid storing it near heat sources or other flammable materials. Proper labeling and documentation are essential for safe storage and handling.