3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide | CAS No. 162401-32-3

3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide

Basic Information

CAS Number

162401-32-3

Molecular Formula

C17H14Cl2F2N2O3

Molecular Weight

403.21 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

157.0 to 161.0 deg-C

Boiling Point

430.6°C at 760 mmHg

Solubility

DMSO: soluble20mg/mL, clear

C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F

InChI

InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)

InChIKey

MNDBXUUTURYVHR-UHFFFAOYSA-N

LogP

5.030900000000003

Topological Polar Surface Area

60.45 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

475

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

  • R0193
  • R03DX07
  • MLS006010074
  • ARQ-151 (roflumilast cream)
  • A24672
  • HMS3748C19
  • HY-15455
  • BY-217
  • APTA 2217
  • roflumilastum
  • AS-14120
  • NCGC00346566-09
  • ARQ-151
  • J-510858
  • n-(3,5-dichloropyridin-4-yl)-4-difluoromethoxy-3-cyclopropylmethoxybenzamide
  • 0P6C6ZOP5U
  • DTXSID8044123
  • ROFLUMILAST [ORANGE BOOK]
  • Roflumilast
  • AMY4219
  • Libertek
  • BDBM14774
  • CCG-268678
  • 162401-32-3
  • HMS3884F09
  • SCHEMBL19158
  • DTXCID6024123
  • s2131
  • Daliresp (TN)
  • Roflumilast- Bio-X
  • ROFLUMILAST [VANDF]

MDL Number

MFCD00938270

FAQ

What is 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3)?

3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3) is a synthetic organic compound with a complex structure containing a benzamide core, cyclopropylmethoxy, and difluoromethoxy groups. It exhibits specific chemical and physical properties, making it relevant in various scientific applications.

What are the main uses of 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3)?

This compound is primarily used in pharmaceutical research for its potential biological activity. It may serve as a lead compound in drug development, particularly in the design of molecules targeting specific enzymes or receptors. Its applications also extend to chemical synthesis and material science research.

Is 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3) safe?

As with many organic compounds, safety precautions should be taken when handling 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3). It is advisable to use personal protective equipment (PPE) such as gloves and goggles. Limited toxicity data is available, but it should be treated as a chemical with potential health and environmental risks.

How should 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3) be stored?

3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide (CAS: 162401-32-3) should be stored in a cool, dry, and dark place, preferably at 2-8°C. It should be kept in a sealed container to prevent moisture and contamination, and away from incompatible substances to ensure stability and safety.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...