![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one | CAS No. 1622-61-3
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Basic Information
CAS Number
1622-61-3
Molecular Formula
C15H10ClN3O3
Molecular Weight
315.71 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
236.5-238.50C
Refractive Index
1.6470 (estimate)
Safety Information
View Safety InformationHazard Statement
H225
Highly Flammable liquid and vapor
Flammable liquids
Flammable liquids
H370
Causes damage to organs
Specific target organ toxicity, single exposure
Specific target organ toxicity, single exposure
Hazard Class
Class 6.1(b)
Class 6.1(b)
Toxicity
LD50 orally in mice: >4000 mg/kg (Blum)
Synonyms & References
English
- clonazepam--dea schedule iv item
- clonazepam methanol solution
- Clonazepam (DD)
- 5-(2-chlorophenyl)-7-nitro-1H-1,4-benzodiazepin-2(3H)-one
- Clonazepam
- ***
- Clonazepam solution
- 5-(2-Chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2(1H)-one
- Clonopin
- Klonopin
- Landsen
- Ribotril
- Rivotri
- Rivotril
- RO4023
- ro4-8180
- ro5-4023
- Sentil
FAQ
What are the physical and chemical properties of 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3)?
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3) is a crystalline compound with a molecular weight of approximately 300.04 g/mol. It has a high solubility in organic solvents such as methanol and ethanol, but is less soluble in water. The compound is reactive, particularly towards nucleophiles and reducing agents. It can be used in various reactions, including substitution and reduction reactions.
How is 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3) typically synthesized?
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3) is typically synthesized through the nitration of 2-chlorophenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. This process involves the use of nitric acid and sulfuric acid as the nitrating mixture. The reaction is conducted under reflux conditions, and the product is isolated and purified through recrystallization.
What industries use 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3)?
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3) is utilized in the pharmaceutical industry for its potential medicinal applications. It can also be used in the development of sensors and as an intermediate in the synthesis of other compounds. Its properties make it relevant in the research and development of new materials, particularly in the field of organic electronics.
What precautions should be taken when handling 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3)?
When handling 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3), it is crucial to follow proper laboratory safety practices. Always wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood. In case of a spill, immediately clean up using appropriate methods and ensure proper disposal. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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