Compound Q&A
How is 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3) typically synthesized?
Answer
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (CAS: 1622-61-3) is typically synthesized through the nitration of 2-chlorophenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. This process involves the use of nitric acid and sulfuric acid as the nitrating mixture. The reaction is conducted under reflux conditions, and the product is isolated and purified through recrystallization.
About
CAS No
1622-61-3
English Name
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Molecular Formula
C15H10ClN3O3
Molecular Weight
315.71 g/mol
SMILES
c1ccc(c(c1)C2=NCC(=O)Nc3c2cc(cc3)[N+](=O)[O-])Cl
InChIKey
DGBIGWXXNGSACT-UHFFFAOYSA-N
Last Updated: 2026-03-17 01:51