Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate

Basic Information

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CAS Number

16205-44-0

Molecular Formula

C10H10N2O2

Molecular Weight

190.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Yellow to Brown Liquid

Boiling Point

134-135 °C/2.3 mmHg

Flash Point

134-135°C/2.3mm

Refractive Index

1.5800

SMILES

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CCOC(=O)C1=C2C=CC=CN2N=C1

InChI

InChI=1S/C10H10N2O2/c1-2-14-10(13)8-7-11-12-6-4-3-5-9(8)12/h3-7H,2H2,1H3

InChIKey

IDHMFSBXNNIWCT-UHFFFAOYSA-N

LogP

1.511

Topological Polar Surface Area

43.599999999999994 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

220

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

CHEMBL2326880
ethyl pyrazolo[1,5-a]pyridine-3-carboxylate
1QP
MFCD06411542
CS-D0884
SY060415
SCHEMBL600704
Pyrazolo[1,5-a]pyridine-3-carboxylic acid, ethyl ester
A810331
AKOS005254487
DTXSID80383686
PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
FT-0650917
Ethylpyrazolo[1,5-a]pyridine-3-carboxylate
SDCCGMLS-0066065.P001
PB29374
W-205891
AM20050857
ethyl H-pyrazolo[1,5-a]pyridine-3-carboxylate
BDBM50490489
IDHMFSBXNNIWCT-UHFFFAOYSA-N
PS-3727
Q27452355
16205-44-0
Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate
ETHYL PYRAZOLO[1,5-A]PYRIDINE-3,4-CARBOXYLATE
Pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester

MDL Number

MFCD06411542

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0)?

Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0) is a crystalline solid with a molecular weight of approximately 238.24 g/mol. It has a solubility of about 0.1 g/100 mL in water and is slightly soluble in common organic solvents like ethanol. The compound is relatively stable under normal conditions but can react with strong bases to form the corresponding anion. It exhibits moderate reactivity towards nucleophiles.

How is Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0) typically synthesized?

Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0) can be synthesized through a multi-step process involving the reaction of ethyl pyrazole-3-carboxylate with 1,5-diazopyridine in the presence of a suitable base. The yield is generally good, and the method is selective. Catalysts such as sodium hydride are often used to enhance reactivity and selectivity.

What industries use Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0)?

Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0) is used in the pharmaceutical industry for its potential as a lead compound in drug discovery. It can also find applications in the synthesis of other compounds, particularly in the development of new materials and sensors. Its properties make it suitable for use in semiconductor and electronic applications as well.

What precautions should be taken when handling Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0)?

When handling Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate (CAS: 16205-44-0), it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be carefully cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.