2-Propyn-1-yl methanesulfonate | CAS No. 16156-58-4

Q: What are the physical and chemical properties of 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4)?

2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) is a colorless liquid with a molecular weight of approximately 136.14 g/mol. It has a density of around 1.03 g/cm³ and is soluble in water and organic solvents. Chemically, it is highly reactive, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis.

Q: How is 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) typically synthesized?

2-Propyn-1-yl methanesulfonate is typically synthesized by the reaction of acrylonitrile with methanesulfonyl chloride in the presence of a base such as triethylamine. This process is known for its high selectivity and yield, making it a common method in the organic synthesis industry.

Q: What industries use 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4)?

2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) is primarily used in the pharmaceutical industry for the synthesis of medicinals and in the polymer industry for the modification of polymer properties. It is also employed in the development of sensors and semiconductors due to its reactivity and solubility.

Q: What precautions should be taken when handling 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4)?

When handling 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood. Spills should be cleaned up with caution, using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.

2-Propyn-1-yl methanesulfonate

Basic Information

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CAS Number

16156-58-4

Molecular Formula

C4H6O3S

Molecular Weight

124.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Nitriles

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

246.7°Cat760mmHg

Density

1.268

Flash Point

>110℃

Refractive Index

1.459

SMILES

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CS(=O)(=O)OCC#C

InChI

InChI=1S/C4H6O3S/c1-3-4-7-8(2,5)6/h1H,4H2,2H3

InChIKey

OWAHJGWVERXJMI-UHFFFAOYSA-N

LogP

-0.01750000000000007

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

187

Safety Information

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Stability

Moisture Sensitive

Synonyms & References

English

SCHEMBL433017
SY226265
2-Propyn-1-yl Methanesulfonate
PROPARGYL METHANESULFONATE ESTER, 95
Propargyl Methanesulfonate Ester, 95per cent
Propargyl methane sulfonate
2-Propyn-1-ol, methanesulfonate
BS-52439
BCP27865
methanesulfonic acid prop-2-ynyl ester; Propargyl Mesylate; 2-Propynyl methanesulfonate; Propargyl methylsulfonate
Propargyl methanesulfonate ester,95
AKOS006329411
FT-0674061
2-propyn-1-ol 1-methanesulfonate
CS-0158537
Prop-2-yn-1-ylmethanesulfonate
METHANESULFONIC ACID PROP-2-YNYL ESTER
NSC-203079
2-propinyl methanesulfonate
propargyl mesylate
MFCD09841205
J-009839
prop-2-yn-1-yl methanesulfonate
NSC203079
s11862
OWAHJGWVERXJMI-UHFFFAOYSA-N
2-propynyl methanesulfonate
2-Propynyl methanesulfonate, >=99.5%, acid <200 ppm, H2O <100 ppm
2-Propyn-1-ol, 1-methanesulfonate
EN300-206238
16156-58-4

MDL Number

MFCD09841205

Customs Code

2905290000

FAQ

What are the physical and chemical properties of 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4)?

2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) is a colorless liquid with a molecular weight of approximately 136.14 g/mol. It has a density of around 1.03 g/cm³ and is soluble in water and organic solvents. Chemically, it is highly reactive, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis.

How is 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) typically synthesized?

2-Propyn-1-yl methanesulfonate is typically synthesized by the reaction of acrylonitrile with methanesulfonyl chloride in the presence of a base such as triethylamine. This process is known for its high selectivity and yield, making it a common method in the organic synthesis industry.

What industries use 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4)?

2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) is primarily used in the pharmaceutical industry for the synthesis of medicinals and in the polymer industry for the modification of polymer properties. It is also employed in the development of sensors and semiconductors due to its reactivity and solubility.

What precautions should be taken when handling 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4)?

When handling 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood. Spills should be cleaned up with caution, using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.