2-Propyn-1-yl methanesulfonate(CAS: 16156-58-4)

2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) is a colorless liquid with a molecular weight of approximately 136.14 g/mol. It has a density of around 1.03 g/cm³ and is soluble in water and organic solvents. Chemically, it is highly reactive, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis.

2-Propyn-1-yl methanesulfonate is typically synthesized by the reaction of acrylonitrile with methanesulfonyl chloride in the presence of a base such as triethylamine. This process is known for its high selectivity and yield, making it a common method in the organic synthesis industry.

2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4) is primarily used in the pharmaceutical industry for the synthesis of medicinals and in the polymer industry for the modification of polymer properties. It is also employed in the development of sensors and semiconductors due to its reactivity and solubility.

When handling 2-Propyn-1-yl methanesulfonate (CAS: 16156-58-4), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood. Spills should be cleaned up with caution, using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.