2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1) | CAS No. 1613220-15-7

2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1)

Basic Information

CAS Number

1613220-15-7

Molecular Formula

C26H30N4O5S

Molecular Weight

510.62 g/mol

AD

Basic Physical Properties

Cc1ccc(cc1)S(=O)(=O)O.c1cc2cn(nc2c(c1)C(=O)N)c3ccc(cc3)[C@@H]4CCCNC4.O

InChI

InChI=1S/C19H20N4O.C7H8O3S.H2O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;1-6-2-4-7(5-3-6)11(8,9)10;/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);2-5H,1H3,(H,8,9,10);1H2/t14-;;/m1../s1

InChIKey

ACNPUCQQZDAPJH-FMOMHUKBSA-N

LogP

3.008420000000002

Topological Polar Surface Area

158.81 Ų

Hydrogen Bond Donor/Acceptor

6 / 9

Complexity

655

Synonyms & References

English

  • Niraparib Tosylate
  • MK-4827, Niraparib TsOH salt hydrate
  • Niraparib tosylate monohydrate
  • Niraparib tosylate hydrate
  • 195Q483UZD
  • (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate
  • Q27252075
  • (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1)
  • 2H-Indazole-7-carboxamide, 2-(4-(3S)-3-piperidinylphenyl)-, 4-methylbenzenesulfonate, hydrate (1:1:1)
  • Zejula

MDL Number

MFCD28167748

FAQ

What is 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (CAS: 1613220-15-7)?

2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate is a derivative of indazole, with piperidine as a substituent. This compound has a complex structure and is used in pharmaceutical research. It features hydrate and salt forms, which contribute to its stability and solubility properties.

What are the main uses of 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (CAS: 1613220-15-7)?

2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate is primarily used in pharmaceutical research for its potential therapeutic effects. It can be utilized as an intermediate or building block in the synthesis of other compounds with similar pharmacological properties.

Is 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (CAS: 1613220-15-7) safe?

The safe handling of 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate requires appropriate precautions. It should be handled in a fume hood and protective equipment should be used. Avoid contact with eyes and skin, and ensure proper ventilation. Spills should be cleaned up carefully and disposed of according to local regulations.

How should 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate (CAS: 1613220-15-7) be stored?

2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to maintain its stability. Ideal storage conditions are between 15-25°C (59-77°F), with a relative humidity below 60%.

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