Bictegravir | CAS No. 1611493-60-7

Bictegravir

Basic Information

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CAS Number

1611493-60-7

Molecular Formula

C21H18F3N3O5

Molecular Weight

449.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Solid powder

Boiling Point

682.5±55.0 °C at 760 mmHg

SMILES

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c1c(cc(c(c1F)CNC(=O)c2cn3c(c(c2=O)O)C(=O)N4[C@H]5CC[C@H](C5)O[C@@H]4C3)F)F

InChI

InChI=1S/C21H18F3N3O5/c22-9-3-14(23)12(15(24)4-9)6-25-20(30)13-7-26-8-16-27(10-1-2-11(5-10)32-16)21(31)17(26)19(29)18(13)28/h3-4,7,10-11,16,29H,1-2,5-6,8H2,(H,25,30)/t10-,11+,16+/m0/s1

InChIKey

SOLUWJRYJLAZCX-LYOVBCGYSA-N

LogP

1.6343999999999999

Topological Polar Surface Area

100.87 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Complexity

912

Synonyms & References

English

Bictegravir
8GB79LOJ07
Bictegravir [INN]
Bictegravir [USAN:INN]
GS 9883
Bictegravir (USAN/INN)
BDBM330048
BCP25703
s5911
DB11799
SB18851
GS-9883
(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide

MDL Number

MFCD31536971

FAQ

What is Bictegravir (CAS: 1611493-60-7)?

Bictegravir (CAS: 1611493-60-7) is an integrase strand transfer inhibitor used in the treatment of HIV-1. It has the chemical formula C21H23FN3O3 and is a white to off-white crystalline powder.

What are the main uses of Bictegravir (CAS: 1611493-60-7)?

Bictegravir (CAS: 1611493-60-7) is primarily used in combination with other antiretroviral drugs to treat HIV-1 infection in adults and adolescents. It helps to reduce the virus to undetectable levels in the blood, thereby improving the patient's immune function.

Is Bictegravir (CAS: 1611493-60-7) safe?

Bictegravir (CAS: 1611493-60-7) is generally considered safe when used as directed. However, it may cause side effects such as headache, nausea, and dizziness. Patients should be monitored for potential interactions with other medications. Consult a healthcare provider for specific safety information.

How should Bictegravir (CAS: 1611493-60-7) be stored?

Bictegravir (CAS: 1611493-60-7) should be stored at room temperature, between 15-30°C (59-86°F), in a tightly closed container, protected from light. Avoid exposure to moisture and heat. Do not freeze the medication.