N,N,N',N'-Tetramethylphosphorodiamidic chloride

Basic Information

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CAS Number

1605-65-8

Molecular Formula

C4H12ClN2OP

Molecular Weight

170.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Agricultural Chemicals Pesticides Insecticides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

110°C/11mmHg

Refractive Index

n20/D 1.466(lit.)

SMILES

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CN(C)P(=O)(N(C)C)Cl

InChI

InChI=1S/C4H12ClN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3

InChIKey

WYLQARGYFXBZMD-UHFFFAOYSA-N

LogP

1.4565

Topological Polar Surface Area

23.550000000000004 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

125

Safety Information

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Hazard Statement

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

SCHEMBL696455
Bis(N,N-dimethylamino)phosphinic chloride
Tetramethylphosphorodiamidoyl chloride
Bis(dimethylamido)phosphoric chloride
NS00025231
N,N,N',N'-tetramethyphosphorodiamidic chloride
InChI=1/C4H12ClN2OP/c1-6(2)9(5,8)7(3)4/h1-4H
N,N,N',N'-Tetramethylphosphorodiamidic chloride
((CH3)2N)2POCl
N-[chloro(dimethylamino)phosphoryl]-N-methylmethanamine
NSC-30697
bis(dimethylamino)phosphorochloridate
bis-(dimethylamino)-phosphochloridate
N-(chloro-dimethylaminophosphoryl)-N-methylmethanamine
Phosphoric Acid Bis(dimethylamido) Chloride
AI3-50985
N,N,N',N'-Tetramethylphosphorodiamidic chloride, technical grade, 90%
EN300-112708
1605-65-8
n,n,n',n'-tetramethyldiamidophosphorochloridate
AKOS016015582
Bis(dimethylamino)phosphoryl Chloride
GEO-03248
CS-0106424
Tetramethyldiamidophosphoryl chloride
TETRAMETHYLPHOSPHORODIAMIDIC CHLORIDE
BAA60565
N,N,N',N'-Tetramethylphosphoro diamidic chloride
NSC30697
Phosphorodiamidic chloride, tetramethyl-
Phosphorodiamidic chloride, N,N,N',N'-tetramethyl-

MDL Number

MFCD00008302

Customs Code

29299090

FAQ

What regulatory guidelines apply to N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8)?

N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8) is subject to various regulatory guidelines. Globally Harmonized System (GHS) classification may include specific handling and storage requirements. In the European Union, REACH regulations require registration and reporting. Additionally, FDA and EPA may have specific requirements for its use in certain applications and its disposal to ensure safety and environmental protection.

Are there alternatives to N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8) in synthesis?

There are alternative reagents that can be used in synthesis instead of N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8). For instance, other phosphoramidites or related phosphorus compounds can serve similar purposes depending on the specific reaction requirements. These alternatives can offer comparable functionalities while possibly differing in reactivity and compatibility.

What is the market or research trend for N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8)?

The market and research trends for N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8) are evolving with increasing interest in its use in oligonucleotide synthesis and drug delivery systems. Recent research focuses on improving its utility in these applications and exploring its potential in emerging fields such as gene therapy and personalized medicine. Demand is expected to grow as these technologies advance.

How should waste containing N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8) be handled?

Waste containing N,N,N',N'-Tetramethylphosphorodiamidic chloride (CAS: 1605-65-8) should be collected in appropriate containers and transported to a facility for safe disposal. Incineration or professional waste disposal services are recommended to ensure complete degradation and minimize environmental impact. Proper precautions should be taken to prevent spills and ensure the waste is handled in accordance with local and international regulations.