3,5-Difluoro-4-pyridinamine

Basic Information

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CAS Number

159783-22-9

Molecular Formula

C5H4F2N2

Molecular Weight

130.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

175°C at 760 mmHg

Density

1.393

Flash Point

59.6°C

Refractive Index

1.524

SMILES

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C1=C(C(=C(C=N1)F)N)F

InChI

InChI=1S/C5H4F2N2/c6-3-1-9-2-4(7)5(3)8/h1-2H,(H2,8,9)

InChIKey

XWAOYJHUAQFFMT-UHFFFAOYSA-N

LogP

0.9420000000000001

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SCHEMBL70438
DTXSID50372209
AKOS005063997
A848140
4-Amino-3,5-difluoropyridine
AS-0054
CS-W005200
3,5-Difluoropyridin-4-amine
3,5-DIFLUORO-PYRIDIN-4-YLAMINE
EN300-1832387
AM20061765
XWAOYJHUAQFFMT-UHFFFAOYSA-N
W-201447
4-PYRIDINAMINE, 3,5-DIFLUORO-
FT-0680826
4-Amino-3,5-difluoropyridine, AldrichCPR
BCP05761
3,5-Difluoro-4-pyridinamine
MFCD01862101
3 pound not5-Difluoropyridin-4-amine
159783-22-9
3,5-difluoropyridin-4-ylamine
SY024909
3,5-Difluoro-pyridin-4-ylamine
3,5-difluoro-4-pyridylamine
difluoropyridinamine
4-Pyridinamine,3,5-difluoro-(9CI)
STL555387
SBB085758
RW2967
BBL101591

MDL Number

MFCD01862101

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9)?

3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9) is a white crystalline solid with a molecular weight of approximately 164.07 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and acetonitrile. It is moderately reactive, particularly towards nucleophiles, and is commonly used in organic synthesis due to its functional groups.

How is 3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9) typically synthesized?

3,5-Difluoro-4-pyridinamine is typically synthesized via the reduction of 3,5-difluoro-4-pyridone using a reducing agent like sodium borohydride. The reaction is carried out in an organic solvent like methanol at room temperature, with good yield and high selectivity.

What industries use 3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9)?

3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9) is primarily used in the pharmaceutical industry for the synthesis of intermediates for drug development. It is also used in the polymer industry for the production of functional polymers with enhanced properties, and in the electronics industry for the development of sensors and semiconductors.

What precautions should be taken when handling 3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9)?

When handling 3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9), it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up using appropriate absorbent materials and the area should be flushed with water. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.