3,5-Difluoro-4-pyridinamine(CAS: 159783-22-9)

CAS Number
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Basic Information
Molecular Formula
C5H4F2N2
Molecular Weight
130.1 g/mol
Physical Properties
Boiling Point
175°C at 760 mmHg
Density
1.393
Flash Point
59.6°C
Chemical Identifiers
SMILES
C1=C(C(=C(C=N1)F)N)F
InChIKey
XWAOYJHUAQFFMT-UHFFFAOYSA-N
Database References
MDL Number
MFCD01862101
FAQ
3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9) is a white crystalline solid with a molecular weight of approximately 164.07 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and acetonitrile. It is moderately reactive, particularly towards nucleophiles, and is commonly used in organic synthesis due to its functional groups.
3,5-Difluoro-4-pyridinamine is typically synthesized via the reduction of 3,5-difluoro-4-pyridone using a reducing agent like sodium borohydride. The reaction is carried out in an organic solvent like methanol at room temperature, with good yield and high selectivity.
3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9) is primarily used in the pharmaceutical industry for the synthesis of intermediates for drug development. It is also used in the polymer industry for the production of functional polymers with enhanced properties, and in the electronics industry for the development of sensors and semiconductors.
When handling 3,5-Difluoro-4-pyridinamine (CAS: 159783-22-9), it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up using appropriate absorbent materials and the area should be flushed with water. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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