N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] | CAS No. 1597403-47-8

N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]

Basic Information

CAS Number

1597403-47-8

Molecular Formula

C22H24Cl2N2O4

Molecular Weight

451.35 g/mol

AD

Basic Physical Properties

Boiling Point

719.0±60.0°C at 760 mmHg

c1c(ccc(c1)Cl)OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc3ccc(cc3)Cl

InChI

InChI=1S/C22H24Cl2N2O4/c23-15-1-9-19(10-2-15)29-13-21(27)25-17-5-7-18(8-6-17)26-22(28)14-30-20-11-3-16(24)4-12-20/h1-4,9-12,17-18H,5-8,13-14H2,(H,25,27)(H,26,28)/t17-,18-

InChIKey

HJGMCDHQPXTGAV-IYARVYRRSA-N

LogP

3.9948000000000023

Topological Polar Surface Area

76.66000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

493

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

  • trans-ISRIB
  • ISRIB trans-isomer
  • ISRIB
  • ISRIB (trans-isomer)
  • N,N'-(cis-Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)
  • N,N'-((1r,4r)-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)
  • N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]
  • 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide
  • 2-(4-chlorophenoxy)-N-(4-{[(4-chlorophenoxy)acetyl]amino}cyclohexyl)acetamide
  • isrib-trans-isomer
  • C7B
  • Oprea1
  • N,N'-(trans-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)

MDL Number

MFCD27952932

FAQ

What regulatory guidelines apply to N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8)?

N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8) falls under the purview of various regulatory guidelines, including the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations, and FDA/EPA requirements. GHS classifies the compound as a hazardous substance due to its toxic properties. REACH regulations require manufacturers to conduct safety assessments and register the substance with the European Chemicals Agency (ECHA). FDA and EPA regulations govern the use and disposal of the compound in the United States, ensuring compliance with environmental and safety standards.

Are there alternatives to N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8) in synthesis?

Alternatives to N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8) in synthesis include various chlorophenol acetamides with different substituents. Common alternative reagents include 2-(4-hydroxyphenoxy)acetamide and 2-(3-chlorophenoxy)acetamide. These alternatives offer similar functionality but with varying physical and chemical properties, making them suitable for different applications based on specific needs and regulatory requirements.

What is the market or research trend for N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8)?

The market for N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8) is characterized by a focus on sustainable and eco-friendly alternatives. Emerging research trends include the development of biodegradable analogs and the exploration of its use in agrochemicals and pharmaceuticals. Market dynamics are driven by increasing environmental concerns and the need for safer alternatives, leading to a shift towards more sustainable compounds and manufacturing processes.

How should waste containing N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8) be handled?

Waste containing N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] (CAS: 1597403-47-8) should be managed according to environmental protection guidelines. Collection of waste liquids should be done in appropriate containers, and disposal should follow local regulations. Incineration or professional waste disposal services are recommended for this hazardous substance. Precautions include proper containment to prevent environmental contamination and the use of personal protective equipment during handling to ensure safety. Compliance with environmental and safety regulations is crucial to minimize the impact on the environment and human health.

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