Azathioprine Impurity 10 (4,5-Dichloroimidazole)

Basic Information

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CAS Number

15965-30-7

Molecular Formula

C3H2Cl2N2

Molecular Weight

136.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

180.0 to 184.0 deg-C

Water Solubility

Insoluble in water.

SMILES

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C1=NC(=C(N1)Cl)Cl

InChI

InChI=1S/C3H2Cl2N2/c4-2-3(5)7-1-6-2/h1H,(H,6,7)

InChIKey

QAJJXHRQPLATMK-UHFFFAOYSA-N

LogP

1.7165

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

YSWG642
MFCD00005195
4,5-dichlorimidazole
1H-Imidazole, 4,5-dichloro-
C3H2Cl2N2
CS-0074351
W-200145
PS-10955
4,5-Dichloroimidazole
4,5-dichloro-1H-imidazole
InChI=1/C3H2Cl2N2/c4-2-3(5)7-1-6-2/h1H,(H,6,7)
AC-27857
D73871
15965-30-7
D2091
QAJJXHRQPLATMK-UHFFFAOYSA-
F0001-0570
A810049
DTXSID30166704
EN300-102203
FT-0617171
QAJJXHRQPLATMK-UHFFFAOYSA-N
NSC 145392
AKOS005255242
NSC145392
SCHEMBL189534
NSC-145392
4,5-Dichloroimidazole, >=98%
GEO-02647
3,4-dichloro-2H-pyrazole
4,5-Dichloro-1H-imidazole

MDL Number

MFCD00005195

Customs Code

2933290090

FAQ

What are the physical and chemical properties of Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7)?

Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7) is a crystalline compound with a molecular weight of approximately 191.02 g/mol. It has a low solubility in water but is more soluble in organic solvents. This compound is moderately reactive, especially in the presence of moisture and heat. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7) typically synthesized?

Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7) is typically synthesized through a multi-step process involving the chlorination of imidazole followed by further reactions. Common catalysts include Lewis acids, and the overall yield is moderate, around 50-70%. The synthesis is conducted under controlled conditions to ensure high selectivity and purity.

What industries use Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7)?

Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of pharmaceuticals. It is also relevant in the polymer industry for the development of certain types of polymers with specific properties. Additionally, this compound can be used in the production of sensors and in some semiconductor applications.

What precautions should be taken when handling Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7)?

When handling Azathioprine Impurity 10 (4,5-Dichloroimidazole) (CAS: 15965-30-7), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Spills should be handled carefully using appropriate absorbents, and the area should be well-ventilated. Work should be conducted in a fume hood to minimize exposure. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.