2-(3-Bromo-4-methoxyphenyl)ethanamine

Basic Information

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CAS Number

159465-27-7

Molecular Formula

C9H12BrNO

Molecular Weight

230.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

114°C 1mm

Refractive Index

n20/D >1.5800(lit.)

Vapor Pressure

0.0±0.6 mmHg at 25°C

SMILES

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COC1=C(C=C(C=C1)CCN)Br

InChI

InChI=1S/C9H12BrNO/c1-12-9-3-2-7(4-5-11)6-8(9)10/h2-3,6H,4-5,11H2,1H3

InChIKey

JHVALSRTUOVNLL-UHFFFAOYSA-N

LogP

1.9588999999999999

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

132

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

2-(3-bromo-4-methoxyphenyl)ethanamine
2-(3-bromo-4-methoxyphenyl)ethan-1-amine
Benzeneethanamine, 3-bromo-4-methoxy-
2-(3-bromo-4-methoxy-phenyl)-ethylamine
F70041
J-009609
159465-27-7
FS-4757
JHVALSRTUOVNLL-UHFFFAOYSA-N
EN300-762925
DTXSID40370810
3-bromo-4-methoxy-phenethyl amine
3-Bromo-4-methoxyphenethylamine
3-bromo-4-methoxyphenethyl amine
MFCD00153891
FT-0676148
2-(3-bromo-4-methoxyphenyl)-ethylamine
SCHEMBL855453
3-Bromo-4-methoxyphenethylamine, 97%
2-(3-bromo-4-methoxyphenyl)ethylamine
AKOS009158648
2-(3-Bromo-4-methoxyphenyl)ethylamine
RARECHEM AL BW 0359
4-(2-AMINOETHYL)-2-BROMOANISOLE
BenzeneethanaMine, 3-broMo-4-Methoxy-
3-Bromo-4-methoxyphenethylamine 97%
3-BROMO-4-METHOXYPHENETHYLAMINE
2-(3-BROMO-4-METHOXYPHENYL)ETHYLAMINE

MDL Number

MFCD00153891

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7)?

2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7) is a colorless to light yellow liquid with a molecular weight of approximately 241.02 g/mol. It has a low solubility in water but is soluble in organic solvents. This compound is reactive towards nucleophiles, particularly towards bromide displacement reactions and nucleophilic aromatic substitution. It is stable under normal conditions but should be stored in a cool, dark place to prevent photodegradation.

How is 2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7) typically synthesized?

2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7) can be synthesized through a bromination reaction of 4-methoxyphenethylamine followed by a nucleophilic aromatic substitution. This process typically involves the use of bromine and a Lewis acid as a catalyst. The yield is generally high, and the reaction is selective for the desired product.

What industries use 2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7)?

2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7) is used in the pharmaceutical industry as a precursor in drug synthesis. It is also utilized in the development of sensors and semiconductors for its specific chemical properties. Due to its role in these industries, it is a key intermediate in the manufacturing of advanced materials and devices.

What precautions should be taken when handling 2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7)?

When handling 2-(3-Bromo-4-methoxyphenyl)ethanamine (CAS: 159465-27-7), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up carefully following standard safety protocols. Always consult the safety data sheet (SDS) for detailed safety information and guidelines.