L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide | CAS No. 158563-45-2

L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide

Basic Information

CAS Number

158563-45-2

Molecular Formula

C61H87N15O9S

Molecular Weight

1206.53 g/mol

AD

Basic Physical Properties

CC(C)[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc3c[nH]c4c3cccc4)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc5ccccc5)NC(=O)[C@@H]6CCCN6C(=O)[C@H](CCSC)N

InChI

InChI=1S/C61H87N15O9S/c1-37(2)51(52(64)77)74-58(83)50-26-16-31-76(50)60(85)45(23-12-13-28-62)70-55(80)46(33-38-17-6-4-7-18-38)71-56(81)48(35-40-36-68-43-22-11-10-21-41(40)43)72-53(78)44(24-14-29-67-61(65)66)69-54(79)47(34-39-19-8-5-9-20-39)73-57(82)49-25-15-30-75(49)59(84)42(63)27-32-86-3/h4-11,17-22,36-37,42,44-51,68H,12-16,23-35,62-63H2,1-3H3,(H2,64,77)(H,69,79)(H,70,80)(H,71,81)(H,72,78)(H,73,82)(H,74,83)(H4,65,66,67)/t42-,44-,45-,46-,47+,48+,49-,50-,51-/m0/s1

InChIKey

KNFLNGRLKALWRF-LDXSYGEZSA-N

LogP

0.49089999999998934

Topological Polar Surface Area

390.53999999999985 Ų

Hydrogen Bond Donor/Acceptor

17 / 24

Complexity

2280

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

  • (Met?,Pro?,D-Phe?,D-Trp?,Phe1?)-α-MSH (5-13)
  • H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
  • Nonapeptide-1
  • Melanostatine-5, Nonapeptide-1
  • (Met?00Pro?00D-Phe?00D-Trp?00Phe??)-α-MSH(5-13)
  • (Met⁵,Pro⁶,D-Phe⁷,D-Trp⁹,Phe¹⁰)-α-MSH (5-13)
  • Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
  • Melitan
  • melanostatine
  • Melanostatine-5
  • Melanostatine-5(nonpeptide-1)
  • Nonapeptide-1, Melanostatine-5, Melanostatine
  • L-Methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide
  • Melitane
  • Nonapeptide-1/Melanostatine
  • BCP25057
  • N-[(2R)-1-[[1-[[1-[[1-[[(2S)-6-Amino-1-[(2S)-2-[(1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl]pyrrolid
  • 64W45420K5
  • (S)-1-(L-methionyl)-N-((R)-1-(((S)-1-(((R)-1-(((S)-1-(((S)-6-amino-1-((S)-2-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxohexan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
  • L-Valinamide, L-methiony

MDL Number

MFCD00672435

FAQ

What is L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide (CAS: 158563-45-2)?

L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valin意识形态 is a complex synthetic peptide with a unique sequence of amino acids, including L and D configurations. Its structure incorporates methionine, proline, phenylalanine, ornithine, tryptophan, lysine, and valine, linked by peptide bonds and a diaminomethylene group. This compound is often studied for its biochemical properties and potential applications in pharmaceutical research.

What are the main uses of L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide (CAS: 158563-45-2)?

This compound is primarily used in pharmaceutical research for studying enzyme inhibition and drug development. It may also serve as a tool in biochemical studies to investigate protein interactions and structural dynamics. Its unique amino acid sequence makes it relevant for applications in biotechnology and as a potential therapeutic agent in advanced research settings.

Is L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide (CAS: 158563-45-2) safe?

The safety of this compound depends on its application and handling. It is generally considered non-toxic in controlled laboratory environments but requires adherence to standard safety protocols to prevent contamination. Precautions include wearing protective gloves and ensuring proper ventilation. Safety standards for its use in pharmaceuticals are typically established through regulatory guidelines and toxicity testing.

How should L-Methionyl-L-prolyl-D-phenylalanyl-N~5~-(diaminomethylene)-L-ornithyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide (CAS: 158563-45-2) be stored?

This compound should be stored in a cool, dry place, away from light, in airtight containers to maintain stability. Refrigeration (2-8°C) is recommended to prevent degradation. Avoid exposure to moisture and high humidity. Proper storage conditions are critical to preserving its structural integrity and ensuring safe handling during experiments or industrial applications.

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