1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione

Basic Information

View in Editor

CAS Number

1585-90-6

Molecular Formula

C6H7NO3

Molecular Weight

141.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

71.0 to 75.0 deg-C

Boiling Point

130°C/0.005mmHg

Flash Point

138.0±23.2 °C

Refractive Index

1.56

Vapor Pressure

0.0±1.4 mmHg at 25°C

SMILES

View in Editor

C1=CC(=O)N(C1=O)CCO

InChI

InChI=1S/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H2

InChIKey

AXTADRUCVAUCRS-UHFFFAOYSA-N

LogP

-1.0963000000000003

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

179

Safety Information

View Safety Information

GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Sensitive to light

Synonyms & References

English

SY055230
FT-0657724
1-(2-hydroxymethyl)-1-H-pyrrole-2,5-dione
EN300-121975
N-2-Hydroxy-ethymaleimide
FD6042
A809944
2-Maleimidylethanol
HY-W017588
N-(2-Hydroxyethyl)maleimide, 97%
1-(2-hydroxyethyl)-2,5-dihydro-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-(2-hydroxyethyl)-
AKOS010455641
SCHEMBL30710
BP-26350
N-(2-hydroxyethyl)maleimide
Z763781306
1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione
MFCD00465266
1-(2-hydroxyethyl)pyrrole-2,5-dione
N-(2hydroxyethyl)maleimide
CS-W018304
1585-90-6
AMY7209
n-2-hydroxyethylmaleimide
DTXSID70332522
InChI=1/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H
AXTADRUCVAUCRS-UHFFFAOYSA-N
2-maleimidyl ethanol
1-(2-Hydroxy-ethyl)-pyrrole-2,5-dione
H1544

MDL Number

MFCD00465266

Customs Code

2925190090

FAQ

What are the physical and chemical properties of 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione (CAS: 1585-90-6)?

1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione is a colorless to pale yellow crystalline solid with a molecular weight of 160.17 g/mol. It has a pKa of 10.5 and is slightly soluble in water. The compound is moderately reactive, showing acidity and can undergo hydrolysis under basic conditions. It does not have significant flammability and has a melting point of 155-157°C.

How is 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione (CAS: 1585-90-6) typically synthesized?

1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione can be synthesized through the condensation of 2-hydroxyethylamine with pyrrole. This reaction is usually catalyzed by an acid or base, and the yield is around 85%. The method involves heating the reactants to promote reaction, and the formation of the product can be monitored by Thin Layer Chromatography (TLC).

What industries use 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione (CAS: 1585-90-6)?

1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione is utilized in various industries including pharmaceuticals for drug synthesis, polymers for monomer production, and sensors for detection of specific analytes. It is also used in the production of semiconductors as a precursor in the manufacturing process.

What precautions should be taken when handling 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione (CAS: 1585-90-6)?

When handling 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione, it is essential to wear protective equipment such as gloves, goggles, and lab coats. The compound should be stored in a cool, dry place away from direct sunlight and moisture. In case of a spill, it should be cleaned up with care using appropriate personal protective equipment, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.