1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione(CAS: 1585-90-6)

1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione is a colorless to pale yellow crystalline solid with a molecular weight of 160.17 g/mol. It has a pKa of 10.5 and is slightly soluble in water. The compound is moderately reactive, showing acidity and can undergo hydrolysis under basic conditions. It does not have significant flammability and has a melting point of 155-157°C.

1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione can be synthesized through the condensation of 2-hydroxyethylamine with pyrrole. This reaction is usually catalyzed by an acid or base, and the yield is around 85%. The method involves heating the reactants to promote reaction, and the formation of the product can be monitored by Thin Layer Chromatography (TLC).

1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione is utilized in various industries including pharmaceuticals for drug synthesis, polymers for monomer production, and sensors for detection of specific analytes. It is also used in the production of semiconductors as a precursor in the manufacturing process.

When handling 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione, it is essential to wear protective equipment such as gloves, goggles, and lab coats. The compound should be stored in a cool, dry place away from direct sunlight and moisture. In case of a spill, it should be cleaned up with care using appropriate personal protective equipment, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.