Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-[(ethoxycarbonyl)oxy]-5-oxopentanoate

Basic Information

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CAS Number

158275-79-7

Molecular Formula

C15H28O7Si

Molecular Weight

348.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

366 °C at 760 mmHg

Density

1.058

Flash Point

145.5 °C

Refractive Index

1.443

SMILES

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CCOC(=O)OC(=O)CC(CC(=O)OC)O[Si](C)(C)C(C)(C)C

InChI

InChI=1S/C15H28O7Si/c1-8-20-14(18)21-13(17)10-11(9-12(16)19-5)22-23(6,7)15(2,3)4/h11H,8-10H2,1-7H3/t11-/m1/s1

InChIKey

BEVABXNTHJECLR-LLVKDONJSA-N

LogP

3.029700000000002

Topological Polar Surface Area

88.13 Å²

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

426

Synonyms & References

English

1-O-ethoxycarbonyl 5-O-methyl (3R)-3-[tert-butyl(dimethyl)silyl]oxypentanedioate
1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate
AKOS015904254
AC-406
Methyl (3R)-3-{[tert-butyl(dimethyl)silyl]oxy}-5-[(ethoxycarbonyl)oxy]-5-oxopentanoate
158275-79-7
Pentanedioic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, monoanhydride with ethyl hydrogen carbonate, methyl ester, (R)- (9CI)
DTXSID20670067
R-(-)-3-(tert-Butyldimethylsilyloxy)glutaric acid monomethyl ester monoethyl carbonate anhydride
1,5-ETHOXYCARBONYL METHYL-(3R)-3-TERT-BUTYL-DIMETHYLSILYLOXY PENTANEDIOATE

MDL Number

MFCD09952324

Customs Code

2931900090

FAQ

What are the physical and chemical properties of Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-[(ethoxycarbonyl)oxy]-5-oxopentanoate (CAS: 158275-79-7)?

The compound has a crystalline form with a molecular weight of approximately 352.43 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can participate in esterification reactions. It is stable under normal conditions but should be stored in a dry environment to avoid hydrolysis.

How is Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-[(ethoxycarbonyl)oxy]-5-oxopentanoate (CAS: 158279-75-7) typically synthesized?

The compound is synthesized via a multi-step process involving silylation and esterification. Commonly, dimethyl(2-methyl-2-propanyl)silane and ethyl chloroacetate are used, catalyzed by a suitable base. The reaction yields are moderate to good, and the product is isolated by recrystallization.

What industries use Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-[(ethoxycarbonyl)oxy]-5-oxopentanoate (CAS: 158275-79-7)?

This compound is primarily used in the pharmaceutical industry for intermediate steps in drug synthesis. It also finds applications in the polymer industry as a stabilizer and in the semiconductor industry for specific chemical processes. Its use in sensors and other advanced technologies is also reported.

What precautions should be taken when handling Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-[(ethoxycarbonyl)oxy]-5-oxopentanoate (CAS: 158275-79-7)?

Handling this compound requires careful attention to safety. Gloves, goggles, and a fume hood should be used to protect against inhalation and skin contact. Spills should be cleaned up with appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.