2-(Aminomethyl)-L-phenylalanine | CAS No. 158149-99-6

2-(Aminomethyl)-L-phenylalanine

Basic Information

CAS Number

158149-99-6

Molecular Formula

C10H14N2O2

Molecular Weight

194.23 g/mol

AD

Basic Physical Properties

C1=CC=C(C(=C1)CC(C(=O)O)N)CN

InChI

InChI=1S/C10H14N2O2/c11-6-8-4-2-1-3-7(8)5-9(12)10(13)14/h1-4,9H,5-6,11-12H2,(H,13,14)/t9-/m0/s1

InChIKey

RDAKEAJYLGZEEA-VIFPVBQESA-N

LogP

0.09970000000000045

Topological Polar Surface Area

89.33999999999999 Ų

Hydrogen Bond Donor/Acceptor

5 / 4

Complexity

197

Synonyms & References

English

  • L-2-Aminomethylphenylalanine (H-L-Phe(2MeNH2)-OH)
  • SCHEMBL1818794
  • 959580-92-8
  • (S)-2-Amino-3-(2-(aminomethyl)phenyl)propanoic acid
  • AKOS026670281
  • MFCD06659114
  • AS-84331
  • (2S)-2-amino-3-[2-(aminomethyl)phenyl]propanoic acid
  • 158149-99-6
  • o-aminomethylphenylalanine
  • 2-(aminomethyl)-L-phenylalanine
  • L-2-Aminomethylphenylalanine
  • L-2-Aminomethylphe
  • starbld0017864
  • DTXSID80376134
  • D-Phenylalanine, a-(aminomethyl)-
  • L-2-AMINOMETHYLPHENYLALANINE
  • L-2-AMINOMETHYLPHE
  • Fmoc-3-(2-Furyl)-L-alanine
  • Fmoc-L-2-FUA
  • Fmoc-β-(2-furyl)-Ala-OH

MDL Number

MFCD06659114

FAQ

What are the physical and chemical properties of 2-(Aminomethyl)-L-phenylalanine (CAS: 158149-99-6)?

2-(Aminomethyl)-L-phenylalanine is a white crystalline solid with a molecular weight of approximately 213.24 g/mol. It has a slight solubility in water and is moderately soluble in organic solvents. Chemically, it is reactive towards carboxylic acids and can undergo peptide bond formation. It is stable under normal storage conditions but requires protection from moisture and light.

How is 2-(Aminomethyl)-L-phenylalanine (CAS: 158149-99-6) typically synthesized?

2-(Aminomethyl)-L-phenylalanine is synthesized by the reaction of phenylalanine with ethylene oxide in the presence of a base like sodium hydroxide. The reaction provides high yield and good selectivity, with the product being isolated by recrystallization from ethanol.

What industries use 2-(Aminomethyl)-L-phenylalanine (CAS: 158149-99-6)?

2-(Aminomethyl)-L-phenylalanine is used in pharmaceuticals for the synthesis of certain drugs and in polymers for the development of functional materials. It is also explored in the sensor and semiconductor industries due to its unique chemical properties.

What precautions should be taken when handling 2-(Aminomethyl)-L-phenylalanine (CAS: 158149-99-6)?

When handling 2-(Aminomethyl)-L-phenylalanine, it is important to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. The compound should be stored in a well-ventilated area and away from moisture. In case of spillage, it should be carefully cleaned up with appropriate absorbent materials, and the area should be flushed with water. The Material Safety Data Sheet (MSDS) should be consulted for detailed guidance.

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