Perifosine | CAS No. 157716-52-4

Perifosine

Basic Information

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CAS Number

157716-52-4

Molecular Formula

C25H52NO4P

Molecular Weight

461.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

271-272° (dec)

Solubility

H2O: soluble10mg/mL, clear

SMILES

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CCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C

InChI

InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3

InChIKey

SZFPYBIJACMNJV-UHFFFAOYSA-N

LogP

8.01730

Complexity

454

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

NSC639966
CHEMBL372764
KRX 0401
Piperidinium, 4-((hydroxy(octadecyloxy)phosphinyl)oxy)-1,1-dimethyl-, inner salt
NSC 639966
NCGC00187909-13
(1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphate
GTPL7424
BCP00245
UNII-2GWV496552
DTXCID0028872
KRX-0401
1,1-dimethylpiperidinium-4-yl octadecyl phosphate
EX-3388
Piperidinium,1-dimethyl-, inner salt
GS-3834
D 21266
DTXSID3048946
P2831
NKA17
CHEBI:67272
NSC-800842
157716-52-4
C25H52NO4P
CCG-269358
AC-25019
CAS-157716-52-4
J-500086
Piperidinium, 4-[[hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethyl-, inner salt
Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
D-21266

MDL Number

MFCD00927554

Customs Code

2933399090

FAQ

What is perifosine (CAS: 157716-52-4)?

Perifosine is an antineoplastic agent with a chemical structure that includes a nitrogen-containing heterocyclic ring. It is used in the treatment of various cancers, particularly those resistant to other therapies.

What are the main uses of perifosine (CAS: 157716-52-4)?

Perifosine is primarily used in the treatment of cancer, specifically in combination with other chemotherapeutic agents to improve response rates and overall survival in patients with advanced or refractory solid tumors.

Is perifosine (CAS: 157716-52-4) safe?

Perifosine can be safe when used under medical supervision. However, it may cause side effects such as nausea, vomiting, and fatigue. Proper dosing and monitoring by healthcare professionals are essential to ensure safety.

How should perifosine (CAS: 157716-52-4) be stored?

Perifosine should be stored in a tightly sealed container at room temperature away from direct sunlight and moisture. It should be protected from light and stored in a cool, dry place to maintain its stability and efficacy.