Pyrazolo[1,5-a]pyridin-5-ol

Basic Information

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CAS Number

156969-42-5

Molecular Formula

C7H6N2O

Molecular Weight

134.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1=CNN2C1=CC(=O)C=C2

InChI

InChI=1S/C7H6N2O/c10-7-2-4-9-6(5-7)1-3-8-9/h1-5,10H

InChIKey

WIKDGUMOUQUAEM-UHFFFAOYSA-N

LogP

1.0398999999999998

Topological Polar Surface Area

37.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

263

Synonyms & References

English

1H-pyrazolo[1,5-a]pyridin-5-one
CS-0139729
Pyrazolo[1,5-a]pyridin-5(1H)-one
SCHEMBL3080966
156969-42-5
AS-47589
Z1198176729
AMY16241
AKOS006230113
F14487
FT-0751754
Pyrazolo[1,5-a]pyridin-5-ol
DTXSID00657634
MFCD08272053
AB44250
WIKDGUMOUQUAEM-UHFFFAOYSA-N
SY020286
EN300-91118
pyrazolo[1,5-a]pyridin-5-ol
pyrazolo<1,5-a>pyridin-5-ol

MDL Number

MFCD08272053

FAQ

What are the physical and chemical properties of Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5)?

Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5) is a white crystalline solid with a molecular weight of approximately 158.16 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is reactive towards nucleophiles and can undergo substitution reactions.

How is Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5) typically synthesized?

Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5) can be synthesized via an intramolecular reaction between a 2-aminopyridine and a 3-nitropyrazole. This reaction requires a suitable base and a suitable solvent, leading to a good yield and high selectivity.

What industries use Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5)?

Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5) is primarily used in the pharmaceutical industry for the development of new drugs. It also finds applications in the synthesis of polymers and as a component in sensors and semiconductors.

What precautions should be taken when handling Pyrazolo[1,5-a]pyridin-5-42-5 (CAS: 156969-42-5)?

Proper personal protective equipment (PPE) is essential when handling Pyrazolo[1,5-a]pyridin-5-ol (CAS: 156969-42-5). This includes gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. In case of spills, use appropriate absorbents and follow the manufacturer's safety data sheet (SDS) guidelines for disposal.