N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

Basic Information

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CAS Number

156648-40-7

Molecular Formula

C31H36N2O6

Molecular Weight

532.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

750.1±60.0°C at 760 mmHg

SMILES

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CC(=NC(CCCCNC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C(=O)O)C4=C(CC(CC4=O)(C)C)O

InChI

InChI=1S/C31H36N2O6/c1-19(28-26(34)16-31(2,3)17-27(28)35)33-25(29(36)37)14-8-9-15-32-30(38)39-18-24-22-12-6-4-10-20(22)21-11-5-7-13-23(21)24/h4-7,10-13,24-25,33H,8-9,14-18H2,1-3H3,(H,32,38)(H,36,37)/t25-/m0/s1

InChIKey

CNDRLQTWKWIHEP-VWLOTQADSA-N

LogP

4.970400000000004

Topological Polar Surface Area

121.80000000000003 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

964

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N'-Fmoc-L-lysine
N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysine
n-alpha-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-n-epsilon-fmoc-l-lysine
CS-0137316
N-alpha-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-epsilon-(9-Fmoc)-L-lysine
DTXSID80679793
156648-40-7
(S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)amino)hexanoic acid
A883554
dde-l-lys(fmoc)-oh
AKOS015911819
F10658
N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)-L-lysine
J-009328
DS-15038
L-Lysine, N2-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-
(2S)-2-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
Dde-Lys(Fmoc)-OH
(2S)-6-(9H-fluoren-9-ylmethoxycarbonylamino)-2-[1-(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)ethylideneamino]hexanoic acid
(S)-6-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino)hexanoic acid
(2S)-2-(1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethylamino)-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
SCHEMBL3502087
MFCD00467662
Dde-L-Lys(Fmoc)-OH
N-α-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-ε-Fmoc-L-lysine
AmbotzDAA1015
DDE-LYSINE(FMOC)-OH
Dde-L-Lys(Fmoc)-OH · solvate
N-α-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)e
N-a-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-e-Fmoc-L-lysine
N-ALPHA-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-N-EPSILON-FMOC-L-LYSINE

MDL Number

MFCD00467662

FAQ

What regulatory guidelines apply to N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7)?

N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7) is subject to regulatory guidelines under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH in the EU, and FDA/EPA requirements for the management of pharmaceutical intermediates. Specific regulations may apply based on the intended use and location of manufacture and use.

Are there alternatives to N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7) in synthesis?

Alternatives to N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7) include other protected amino acids or synthetic intermediates that can serve similar functional groups. Common alternatives include protected lysine derivatives with different protecting groups or other specific functional groups that can be used in similar chemical reactions.

What is the market or research trend for N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7)?

The market for N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7) is driven by its applications in pharmaceuticals and organic synthesis. Research trends focus on its utility in drug discovery, as a precursor in peptide and protein synthesis, and in the development of new protective groups for amino acids. The trend shows increasing interest in its use as a versatile reagent in academic and industrial settings.

How should waste containing N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7) be handled?

Waste containing N~2~-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 156648-40-7) should be collected in appropriate containers and disposed of according to local regulations. Typically, this involves incineration or professional waste disposal services that comply with hazardous waste management guidelines. Environmental protection measures include careful handling to prevent spills and ensure proper waste treatment to minimize environmental impact.