Alvimopan | CAS No. 156053-89-3

Alvimopan

Basic Information

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CAS Number

156053-89-3

Molecular Formula

C25H32N2O4

Molecular Weight

424.54 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

684.1 °C at 760 mmHg

Density

1.166

Flash Point

367.5°C

Refractive Index

1.572

SMILES

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CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O

InChI

InChI=1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1

InChIKey

UPNUIXSCZBYVBB-JVFUWBCBSA-N

LogP

3.051400000000001

Topological Polar Surface Area

89.87 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

606

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Synonyms & References

English

Glycine, N-[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-
NS00069226
UNII-Q153V49P3Z
AS-35088
Q153V49P3Z
NG0
HY-13243
(((2S)-2-(((3R,4R)-4-(3-HYDROXYPHENYL)-3,4-DIMETHYLPIPERIDIN-1-YL)METHYL)-3-PHENYLPROPANOYL)AMINO)ACETIC ACID
Adl 8-2698
N-[(2S)-2-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl}-3-phenylpropanoyl]glycine
NCGC00378640-01
145590-44-9
Glycine, N-((2S)-2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-1-oxo-3-phenylpropyl)-
2-[[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl]-3-phenylpropanoyl]amino]acetic acid
156053-89-3
NCGC00378640-02
2-((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)aceticacid
anhydrous alvimopan
Alvimopan
LY-246736
Q4738021
((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycine
ANHYDROUS ALVIMOPAN [MART.]
GTPL7471
SR-01000945029-1
N-((2S)-2-(((3R,4R)-4-(3-HYDROXYPHENYL)-3,4-DIMETHYL-1-PIPERIDINYL)METHYL)-1-OXO-3-PHENYLPROPYL)GLYCINE
ALVIMOPAN [MART.]
BDBM50088381
Entereg
DB06274
LY-246736 dihydrate

MDL Number

MFCD09838268

Customs Code

2933399090

FAQ

What regulatory guidelines apply to Alvimopan (CAS: 156053-89-3)?

Alvimopan (CAS: 156053-89-3) is subject to regulatory guidelines under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) in the EU, and FDA/EPA requirements in the USA. Compliance with these regulations ensures safe handling, storage, and disposal of the compound.

Are there alternatives to Alvimopan (CAS: 156053-89-3) in synthesis?

Alternatives to Alvimopan (CAS: 156053-89-3) in synthesis include other gastrointestinal motility agonists such as cisapride and tegaserod. Researchers often explore these alternatives due to varying efficacy and safety profiles, though Alvimopan is specifically designed for postoperative ileus and opioid-induced bowel dysfunction.

What is the market or research trend for Alvimopan (CAS: 156053-89-3)?

The market for Alvimopan (CAS: 156053-89-3) has shown steady growth due to its application in managing postoperative ileus and opioid-induced bowel dysfunction. Research trends focus on understanding its mechanism of action, potential side effects, and comparative efficacy with other gastrointestinal motility agents.

How should waste containing Alvimopan (CAS: 156053-89-3) be handled?

Waste containing Alvimopan (CAS: 156053-89-3) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration or chemical decontamination may be necessary, and environmental protection measures should be followed to prevent contamination of water and soil.