Abiraterone | CAS No. 154229-19-3

Abiraterone

Basic Information

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CAS Number

154229-19-3

Molecular Formula

C24H31NO

Molecular Weight

349.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

No data available

Melting Point

226.0 to 230.0 deg-C

Boiling Point

500°C at 760 mmHg

Density

1.14

Flash Point

256.3°C

Solubility

DMSO 0.1 mg/mL Water 0.02 mg/mL Ethanol 0.2 mg/mL

Refractive Index

1.605

SMILES

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C[C@@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]2CC=C1c5cccnc5

InChI

InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1

InChIKey

GZOSMCIZMLWJML-VJLLXTKPSA-N

LogP

5.398600000000005

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

636

Safety Information

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Hazard Statement

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Synonyms & References

English

(3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol
17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
Androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, (3beta)-
Cb 7598
Cb-7598
Unii-G819A456D0
Abiraterone(CB-7598)
(3S,8R,9S,10R,13S,14S)-10,13-diMethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
abiraterone
17-(3-Pyridyl)androsta-5,16-dien-3β-ol
Aberration
Acetyl Abiraterone
Prasteronyl Abiraterone
3-epi-Abiraterone Acetate
G819A456D0
(3S,8R,9S,10R,13R,14R)-10,13-Dimethyl-16-pyridin-3-yl-2,3,4,7,8,9,11,12,14,17-decahydro-1H-cyclopent
AbirateroneRefrigerator
CB-7598
Abiraterone
CB 7598
Abiraterone, >=98%
(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

MDL Number

MFCD00924100

FAQ

What is Abiraterone (CAS: 154229-19-3)?

Abiraterone is a synthetic steroid compound with the chemical formula C21H26N2O. It is known for its ability to inhibit the enzyme CYP17, which plays a key role in the production of androgens. This compound is widely used in medical research and pharmaceutical applications due to its potent anti-androgenic properties.

What are the main uses of Abiraterone (CAS: 154229-19-3)?

Abiraterone is primarily used in the treatment of prostate cancer and certain types of breast cancer. It functions as an androgen synthesis inhibitor, helping to reduce testosterone levels in the body. Additionally, it is utilized in research for studying hormonal pathways and developing new therapeutic agents.

Is Abiraterone (CAS: 154229-19-3) safe?

Abiraterone is generally considered safe when used as directed in medical treatments. However, it may cause side effects such as fatigue, hypertension, and fluid retention. Proper handling and adherence to safety guidelines are essential, especially in laboratory settings, to minimize risks to health and the environment.

How should Abiraterone (CAS: 154229-19-3) be stored?

Abiraterone should be stored in a cool, dry, and dark place, ideally at 20-25°C. It is sensitive to moisture and light, so it should be kept in a sealed container. Proper storage ensures the stability and potency of the compound for extended periods.