Amikacin Impurity 5

Basic Information

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CAS Number

154-58-5

Molecular Formula

C6H12O5

Molecular Weight

164.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White cryst.

Melting Point

157 ºC

Boiling Point

376.8 ºC at 760 mmHg

Flash Point

181.7 ºC

Refractive Index

1.581

SMILES

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O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1

InChI

InChI=1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2/t3-,4+,5+,6+/m0/s1

InChIKey

MPCAJMNYNOGXPB-SLPGGIOYSA-N

LogP

-2.5398000000000005

Topological Polar Surface Area

90.15 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

128

Safety Information

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Hazard Statement

Synonyms & References

English

1,5-ANHYDRO-D-GLUCITOL
1,5-anhydroglucitol
1,5-ANHYDRO-D-SORBITOL
D-Glucitol, 1,5-anhydro-
(2R,3R,4R,5S)-2-(hydroxymethyl)oxane-3,4,5-triol
1,5-Anhydrosorbitol
1-Deoxy-D-glucopyranose
1,5-ANHYDRO-D-SORBITOL CRYSTALLINE
1,5-Sorbitan
1-Deoxy-D-glucose
Aceritol
Polygalitol
1-Deoxyglucose
1,5-Anhydro-D-glucitol
1,5-Anhydroglucitol
1-Deoxy-D-Glucose
(2R,3S,4R,5S)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

MDL Number

MFCD00067386

Customs Code

2932999099

FAQ

What regulatory guidelines apply to Amikacin Impurity 5 (CAS: 154-58-5)?

Amikacin Impurity 5 (CAS: 154-58-5) is subject to the regulations of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes specific hazard classification, labeling, and safety data sheets. Under the European Union's Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation, manufacturers and importers must register the compound with the European Chemicals Agency (ECHA). In the United States, the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) may require additional registration and testing under certain conditions.

Are there alternatives to Amikacin Impurity 5 in synthesis?

Alternative reagents to Amikacin Impurity 5 (CAS: 154-58-5) can include similar amikacin analogs or other aminoglycoside antibiotics with similar biochemical properties, such as neomycin or tobramycin. These alternatives may be used depending on the specific synthesis requirements, availability, and cost considerations.

What is the market or research trend for Amikacin Impurity 5?

Research trends for Amikacin Impurity 5 (CAS: 154-58-5) focus on its role as a byproduct of the production of the antibiotic amikacin. Market trends indicate a steady demand for accurate quantification of impurities to ensure product quality and regulatory compliance. Emerging research is exploring the potential use of these impurities in developing new therapeutic agents or as markers for quality control purposes.

How should waste containing Amikacin Impurity 5 be handled?

Waste containing Amikacin Impurity 5 (CAS: 154-58-5) should be collected in appropriate containers and stored in a secure location until disposal. Proper incineration or professional waste disposal services should be utilized to ensure safe and compliant disposal. Environmental protection precautions include ensuring no spillage and following local environmental regulations for hazardous waste management.