3-(Trifluoromethoxy)aniline

Basic Information

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CAS Number

1535-73-5

Molecular Formula

C7H6F3NO

Molecular Weight

177.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

72～73℃/8mmHg

Boiling Point

70°C/7mmHg

Water Solubility

Not miscible or difficult to mix in water.

Refractive Index

n20/D 1.466(lit.)

SMILES

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C1=CC(=CC(=C1)OC(F)(F)F)N

InChI

InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-2-5(11)4-6/h1-4H,11H2

InChIKey

SADHVOSOZBAAGL-UHFFFAOYSA-N

LogP

2.1673999999999998

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

148

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class Comb liq Class Comb liq

Sensitiveness

Sensitive to light, sensitive to air

Synonyms & References

English

SY002366
FT-0613898
3-(trifluoromethoxy)-aniline
3-trifluoromethoxy-phenylamine
AKOS005145725
AC-3707
AM20050523
T2255
[3-(trifluoromethoxy)phenyl]amine
Z278206764
3-trifluoromethoxy aniline
3-(trifluoromethoxyl)benzenamine
m-Aminophenyl trifluoromethyl ether
QUPWXXHMPXWWKS-UHFFFAOYSA-N
3-(Trifluoromethoxy) aniline
SCHEMBL1523
1535-73-5
alpha,alpha,alpha-Trifluoro-m-anisidine
UNII-AZ5VZ8MT94
3-(Trifluoromethoxy)aniline
m-(trifluoromethoxy)aniline
3-(Trifluoromethoxy)aniline, 98%
m-trifluoromethoxyaniline
3-(trifluoromethoxy)benzenamine
MFCD00041511
CS-W017377
DTXSID60165341
meta-trifluoromethoxy-phenylamine
SDCCGMLS-0066230.P001
3-trifluoromethoxy-aniline
Q-200332

MDL Number

MFCD00041511

Customs Code

29222900

FAQ

What regulatory guidelines apply to 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5)?

3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) falls under the regulatory guidelines of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). It is classified as a hazardous substance under the European Union's REACH regulations. In the United States, it may be subject to regulations by the EPA and FDA for environmental and safety reasons. Proper handling and disposal must comply with local and national laws.

Are there alternatives to 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) in synthesis?

Several alternatives to 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) can be used in synthesis, depending on the specific application. Common alternatives include other anilines with different substituents, such as 4-(trifluoromethyl)aniline. These alternatives can be selected based on reactivity, availability, and cost.

What is the market or research trend for 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5)?

3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) is increasingly being studied in various research fields due to its unique properties, such as its ability to form stable complexes. Market trends show an increasing demand in pharmaceuticals and materials science, where it is used as a precursor for drug synthesis and functional materials. However, its hazardous nature requires careful handling and disposal.

How should waste containing 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) be handled?

Waste containing 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration can be an effective method, but it must be conducted in a controlled environment to prevent environmental contamination. Proper environmental protection measures, such as minimizing emissions and ensuring compliance with local regulations, are essential.