Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-

Basic Information

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CAS Number

15318-45-3

Molecular Formula

C12H15Cl2NO5S

Molecular Weight

356.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

164.0 to 168.0 deg-C

Boiling Point

695.9±55.0 °C at 760 mmHg

Water Solubility

Soluble in acetonitrile or DMF. Slightly soluble in water

Flash Point

374.7±31.5 °C

Solubility

ethanol: 50 mg/mL, clear, colorless

Refractive Index

1.6000 (estimate)

Specific Rotation

D25 +12.9° (ethanol)

SMILES

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OC[C@H]([C@@H](c1ccc(cc1)S(=O)(=O)C)O)NC(=O)C(Cl)Cl

InChI

InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1

InChIKey

OTVAEFIXJLOWRX-NXEZZACHSA-N

LogP

0.40429999999999977

Topological Polar Surface Area

103.69999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

443

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

thiamphenicol
methylsulfonyl chloramphenicol
D-THREO-2,2-DICHLORO-N-(BETA-HYDROXY-ALPHA-[HYDROXYMETHYL]-4-[METHYLSULFONYL]PHENETHYL)ACETAMIDE
D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-P-(METHYL-SULFONYL)PHENETHYL]ACETAMIDE
8065c.b.
acetamide,2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl
dextrosulphenidol
thiocymetin
2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]-2-propyl]acetamide
D-Thiocymetin
D-Thiophenicol
Neomyson
THIAMPHENICHOL
thiophenicol
win-5063-2
NSC 522822
Thiamcol
(+)-Thiamphenicol
Raceophenidol
Thiamphenicolum
Thiocymetin (TN)
Armai (TN)
Tiamfenicolo [DCIT]
Tiamfenicol [INN-Spanish]
Thiamphenicol (Thiophenicol)
Macphenicol
Masatirin
Efnicol
Rincrol
Urfamicina
Thiamphenicolum [INN-Latin]

MDL Number

MFCD00467983

Customs Code

2941400000

FAQ

What is Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3)?

Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3) is an organic compound with the chemical formula C15H16Cl2NO5S. It is a white to off-white solid with moderate solubility in water and organic solvents. This compound is characterized by its acetic acid amide functionality and a complex branched structure containing chlorine, hydroxyl, and methylsulfonyl groups.

What are the main uses of Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3)?

Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3) is primarily used in pharmaceutical research as an intermediate in the synthesis of various drugs. It may also find applications in chemical synthesis processes and as a component in specialty chemical products due to its versatile functional groups and reactivity.

Is Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3) safe?

Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3) is generally considered safe when handled properly. It should be used with appropriate protective equipment, such as gloves and goggles, to avoid direct contact. Safety data sheets (SDS) should be consulted for detailed handling and exposure guidelines to ensure compliance with safety regulations.

How should Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3) be stored?

Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl] (CAS: 15318-45-3) should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is best kept in a sealed container to prevent moisture absorption and maintain stability. Avoid exposure to incompatible materials to ensure safe storage conditions.