Fluocortolone

Basic Information

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CAS Number

152-97-6

Molecular Formula

C22H29FO4

Molecular Weight

376.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

113-116°C

Specific Rotation

D20 +100° (dioxane)

SMILES

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CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1C(=O)CO)C)O)C)F

InChI

InChI=1S/C22H29FO4/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-21(15,2)20(13)17(26)9-22(14,3)19(11)18(27)10-24/h4-5,7,11,13-14,16-17,19-20,24,26H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20-,21+,22+/m1/s1

InChIKey

GAKMQHDJQHZUTJ-ULHLPKEOSA-N

LogP

2.6367000000000016

Topological Polar Surface Area

74.6 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

743

Synonyms & References

English

Fluocortolona [INN-Spanish]
Fluocortolon
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16-methyl-, (6alpha,11beta,16alpha)-
FLUOCORTOLONE [INN]
FLUOCORTOLONE
BCP0726000096
D04218
Fluocortolone (USAN/INN)
6-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
Q5462793
(6alpha,11beta,16alpha)-6-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
BCP9000698
6-alpha-Fluoro-16-alpha-methyl-delta(sup 1,4)-pregnadiene-11-beta-diol-3,20-dione
FLUOCORTOLONE [MI]
Fluocortolona
SCHEMBL4644
Fluocortolone [USAN:INN:BAN]
FLUOCORTOLONE [WHO-DD]
2-ethyl-quinazolin-4-ol
FLUOCORTOLONE [MART.]
SH-742
EN300-19767700
Fluorocortolone
EINECS 205-811-5
FLUOCORTOLONE [JAN]
6-alpha-Fluoro-16-alpha-methylpregna-1,4-diene-11-beta,21-diol-3,20-dione
CHEBI:135581
BRN 3122594
J-008966
FLUOCORTOLONE [USAN]

MDL Number

MFCD00867463

Customs Code

2942000000

FAQ

What is Fluocortolone (CAS: 152-97-6)?

Fluocortolone (CAS: 152-97-6) is a synthetic corticosteroid used in dermatological applications for its anti-inflammatory and immunosuppressive properties. It is available as a topical cream or ointment and is known for its effectiveness in treating various skin conditions like eczema, psoriasis, and dermatitis.

What are the main uses of Fluocortolone (CAS: 152-97-6)?

Fluocortolone (CAS: 152-97-6) is primarily used as a topical corticosteroid to treat inflammatory and immunological skin conditions such as eczema, psoriasis, and dermatitis. It is also used to reduce inflammation and itching associated with various dermatological disorders.

Is Fluocortolone (CAS: 152-97-6) safe?

Fluocortolone (CAS: 152-97-6) is safe when used as directed by a healthcare professional. However, prolonged or extensive use can lead to side effects such as thinning of the skin, acne, and increased susceptibility to infections. It is important to follow the prescribed dosage and instructions to minimize risks.

How should Fluocortolone (CAS: 152-97-6) be stored?

Fluocortolone (CAS: 152-97-6) should be stored in a tightly sealed container at room temperature (15-30°C or 59-86°F) and away from direct sunlight and moisture. Ensure that the product is kept out of reach of children and pets. Store the medication in a cool, dry place to maintain its efficacy and stability.