Betamethasone 21-Phosphate Disodium Salt

Basic Information

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CAS Number

151-73-5

Molecular Formula

C22H28FNa2O8P

Molecular Weight

516.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Insecticides

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Boiling Point

669.6 oC at 760 mmHg

Flash Point

358.7oC

SMILES

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CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]

InChI

InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1

InChIKey

PLCQGRYPOISRTQ-LWCNAHDDSA-L

LogP

2.88910

Complexity

962

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

NSC 90616
UNII-7BK02SCL3W
CELESTONE SOLUSPAN COMPONENT BETAMETHASONE SODIUM PHOSPHATE
Bentelan
AKOS015896371
BETAMETHASONE SODIUM PHOSPHATE [VANDF]
CHEBI:3078
disodium;[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
beta-Methasone sodium phosphate
Tox21_302467
Linosal
Betamethasone 21-phosphate disodium
BETAMETHASONE SODIUM PHOSPHATE [EP MONOGRAPH]
beta-Methasone, disodium phosphate
Bentelan; Betamethasone 21-disodium phosphate; Betamethasone 21-phosphate disodium salt; Betamethasone disodium phosphate
BETAMETHASONE SODIUM PHOSPHATE [JAN]
beta-Methasone disodium phosphate
BETAMETHASONE SODIUM PHOSPHATE (USP-RS)
BETAMETHASONE SODIUM PHOSPHATE [USP MONOGRAPH]
AS-62442
SCHEMBL8418
BETAMETHASONE SODIUM PHOSPHATE [ORANGE BOOK]
Betamethasone sodium phosphate, European Pharmacopoeia (EP) Reference Standard
151-73-5
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-
Betamethasone 21-phosphate disodium, >=97%
Betamethasone 21-phosphate sodium
DTXCID6027137
NSC-90616
B4110
Betamethazone disodium phosphate

MDL Number

MFCD00200361

Customs Code

2937229000

FAQ

What is Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5)?

Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5) is a corticosteroid derivative used primarily in pharmaceutical applications. It has the chemical formula C23H28F2Na2O9P and is characterized by its phosphate ester group, which enhances its stability and bioavailability. This compound is commonly used as a prodrug for betamethasone, a potent anti-inflammatory agent, and is available in various formulations for medical use.

What are the main uses of Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5)?

Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5) is primarily used in the pharmaceutical industry as a prodrug for betamethasone. It is employed in topical and systemic treatments for inflammation, allergies, and autoimmune conditions. Additionally, it is used in research for studying corticosteroid metabolism and in the development of new therapeutic formulations. Its phosphate structure makes it suitable for controlled release applications.

Is Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5) safe?

Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5) is generally considered safe when used as directed in medical and research settings. However, it should be handled with care, as prolonged exposure may pose health risks. Safety standards recommend using appropriate personal protective equipment (PPE) and following guidelines for storage and disposal. In clinical use, it is subject to regulatory oversight to ensure patient safety and efficacy.

How should Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5) be stored?

Betamethasone 21-Phosphate Disodium Salt (CAS: 151-73-5) should be stored in a cool, dry place away from direct light. The recommended temperature range is between 15°C to 25°C (59°F to 77°F). It is important to keep the container tightly sealed to prevent moisture ingress and maintain stability. Proper storage ensures the compound remains effective and safe for use in pharmaceutical and research contexts.