2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole

Basic Information

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CAS Number

15082-28-7

Molecular Formula

C24H22N2O

Molecular Weight

354.45 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

136.0 to 138.0 deg-C

Boiling Point

505.1ºC at 760 mmHg

Density

1.1030

Flash Point

505.1 °C at 760 mmHg

Solubility

toluene: 0.1 g/mL, clear, colorless

Refractive Index

1.579

SMILES

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CC(C)(C)C1=CC=C(C=C1)C2=NN=C(O2)C3=CC=C(C=C3)C4=CC=CC=C4

InChI

InChI=1S/C24H22N2O/c1-24(2,3)21-15-13-20(14-16-21)23-26-25-22(27-23)19-11-9-18(10-12-19)17-7-5-4-6-8-17/h4-16H,1-3H3

InChIKey

XZCJVWCMJYNSQO-UHFFFAOYSA-N

LogP

6.368100000000005

Topological Polar Surface Area

38.92 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

452

Safety Information

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Hazard Statement

Synonyms & References

English

1,4-Oxadiazole, 2-[1,1'-biphenyl]-4-yl-5-[4-(1,1-dimethylethyl)phenyl]-
InChI=1/C24H22N2O/c1-24(2,3)21-15-13-20(14-16-21)23-26-25-22(27-23)19-11-9-18(10-12-19)17-7-5-4-6-8-17/h4-16H,1-3H
tert-Butylphenyl-p-biphenyloxadiazole
YKR9AP6LRZ
1,4-Oxadiazole, 2-(4-biphenylyl)-5-(p-tert-butylphenyl)-
Tert-Butyl PBD
Butyl-PBD
2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole
PS-6991
2-[1,1'-Biphenyl]-4-yl-5-(4-tert-butylphenyl)-1,3,4-oxadiazole #
2-(t-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole
NSC-158164
XZCJVWCMJYNSQO-UHFFFAOYSA-N
B2696
butyl pbd
EINECS 239-135-7
b-PBD
AKOS003575241
FT-0696266
2-(4-biphenylyl)-5-(p-tert-butylphenyl)-1,3,4-oxadiazole
15082-28-7
MFCD00003101
2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole, (purified by sublimation)
2-(4-tert-butylphenyl)-5-(4-phenylphenyl)-1,3,4-oxadiazole
2-{[1,1'-biphenyl]-4-yl}-5-(4-tert-butylphenyl)-1,3,4-oxadiazole
1,3,4-Oxadiazole, 2-(4-biphenylyl)-5-(p-tert-butylphenyl)-
UNII-YKR9AP6LRZ
5-(4-tert-butylphenyl)-2-(biphenyl-4-yl)-1,3,4-oxadiazole
2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole (purified by sublimation)
NSC158164
2-(4-Biphenyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole

MDL Number

MFCD00003101

Customs Code

2934999090

FAQ

What regulatory guidelines apply to 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7)?

2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7) should comply with the Globally Harmonized System (GHS) for classification and labeling of chemicals. Under REACH regulations, it may require registration if its manufacture or import exceeds certain quantities. FDA and EPA guidelines govern its use and disposal in the United States, ensuring it meets toxicological and environmental safety standards.

Are there alternatives to 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7) in synthesis?

In synthesis, 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7) can be replaced with similar oxadiazoles or other heterocycles like thiadiazoles. Common alternatives include 1,3,4-thiadiazoles and 1,2,4-triazoles, which offer similar functional properties and can be used as intermediates in various organic synthesis reactions.

What is the market or research trend for 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7)?

The market for 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7) is growing due to increasing demand in pharmaceuticals and materials science. Research trends include its application in drug discovery and development, particularly in antiviral and anticancer therapies. Additionally, there is a trend towards developing sustainable synthesis methods to reduce environmental impact.

How should waste containing 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7) be handled?

Waste containing 2-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-1,3,4-oxadiazole (CAS: 15082-28-7) should be collected in appropriate containers and stored in a secure location. Incineration is a common method for disposal, but it must be conducted at a certified facility to meet environmental safety standards. Alternatively, professional waste disposal services can handle the waste, ensuring it is treated according to regulatory requirements and environmental protection measures.