4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine

Basic Information

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CAS Number

150728-13-5

Molecular Formula

C15H10Cl2N4O2

Molecular Weight

349.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

157.0 to 161.0 deg-C

Boiling Point

520.7℃ at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

197.0±16.1 °C

Refractive Index

1.617

Vapor Pressure

0.0±0.9 mmHg at 25°C

SMILES

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COC1=CC=CC=C1OC2=C(N=C(N=C2Cl)C3=NC=CC=N3)Cl

InChI

InChI=1S/C15H10Cl2N4O2/c1-22-9-5-2-3-6-10(9)23-11-12(16)20-15(21-13(11)17)14-18-7-4-8-19-14/h2-8H,1H3

InChIKey

IZGOBGVYADHVKH-UHFFFAOYSA-N

LogP

4.041300000000002

Topological Polar Surface Area

70.02000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

361

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-dipyrimidine
SB57954
SY030948
AC-4272
UNII-SLW8S7AP2H
2,2'-bipyrimidine, 4,6-dichloro-5-(2-methoxyphenoxy)-
4,6-dichloro-5-(2-methoxy-phenoxy) -[2,2']bipyrimidine
DTXSID40441594
4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine;Bosentan Intermediates
EN300-7374534
4,6-dichloro-5-(2-methoxy-phenoxy)-[2,2']bipyrimidine
BCP08842
4,6-dichloro-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidine
SLW8S7AP2H
FT-0603692
4,6-dichloro-5-(2-methoxy-phenoxy)-2,2'-bipyrimidine
4,6-Dichloro-5-(2-methoxyphenoxy)-2,2 inverted exclamation mark -bipyrimidine
4,6-dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-pyrimidine
4,6-dichloro-5-(2-methoxyphenoxy)-2,2-bipyrimidine
A13929
4,6-dichloro-5-(methoxyphenoxy)-2,2-bipyrimidinyl
4,6-dichloro-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)-pyrimidine
J-514130
4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
IZGOBGVYADHVKH-UHFFFAOYSA-N
150728-13-5
SCHEMBL618135
5-(2-Methoxyphenoxy)-4,6-dichloro-2-(2-pyrimidinyl)pyrimidine
4,6-dichloro-5-(2-methoxyphenoxy)2,2'-bipyrimidine
CS-B0151
4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidinyl

MDL Number

MFCD03839838

Customs Code

2933599090

FAQ

What regulatory guidelines apply to 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine (CAS: 150728-13-5)?

4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine is classified under GHS as a hazardous substance due to its potential health and environmental hazards. It must comply with REACH regulations in the EU, including registration, evaluation, and authorization for substances of very high concern. In the US, it is subject to FDA and EPA regulations for safety and environmental protection, including reporting of releases and disposal methods.

Are there alternatives to 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine in synthesis?

There are several alternatives in the synthesis of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine. For instance, 4,6-Dichloro-2,2'-bipyrimidine can be used as a precursor. Additionally, other bipyrimidine derivatives like 4,6-dichloro-2,2'-bipyrimidine-5-carbonitrile can be explored as alternatives depending on the specific application and desired properties.

What is the market or research trend for 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine?

The market for 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine is growing, driven by its applications in the pharmaceutical industry. Research trends focus on its use as a dopant in organic electronic devices and as a potential antiparasitic agent. However, the market is also facing challenges related to regulatory compliance and the need for safer alternatives due to its hazardous nature.

How should waste containing 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine be handled?

Waste containing 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine should be collected in a sealed, labeled container and disposed of according to local and international hazardous waste regulations. Safe incineration is recommended, and professional waste disposal services should be used. Proper environmental protection measures, such as ventilation and protective equipment, must be observed during handling to prevent exposure and environmental contamination.