4-Aminobenzoic acid

Basic Information

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CAS Number

150-13-0

Molecular Formula

C7H7NO2

Molecular Weight

137.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

187-189 °C

Boiling Point

339.9°C at 760 mmHg

Water Solubility

4.7 g/L (20 ºC)

Flash Point

159.4℃

Solubility

95% ethanol: soluble5%, clear to slightly hazy, colorless to yellow

Refractive Index

1.5323 (estimate)

SMILES

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Nc1ccc(cc1)C(=O)O

InChI

InChI=1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)

InChIKey

ALYNCZNDIQEVRV-UHFFFAOYSA-N

LogP

0.9670000000000001

pKa

2.50, 4.87(at 25℃)

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

128

Safety Information

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GHS Hazard Pictograms

H315

H317

H319

H335

H413

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H413 May cause long lasting harmful effects to aquatic life
Hazardous to the aquatic environment, long-term hazard

Stability

Stable. Incompatible with strong oxidizing agents. Combustible. Sensitive to light and air. May discolour on exposure to light.

Sensitiveness

Air & Light Sensitive

Toxicity

LD50 in mice, rats (g/kg): 2.85, >6.0 orally (Scott, Robbins); LD50 in rabbits (g/kg): 2.0 i.v. (Richards); 1.83 orally (Cronheim)

Synonyms & References

English

1-Amino-4-carboxybenzene
4-CARBOXYANILINE
AMINOBENZOIC-4 ACID
AMINOBENZOIC ACID
ANTICANITIC VITAMIN
BACTERIAL VITAMIN H1
CHROMOTRICHIA FACTOR
H-4-ABZ-OH
PABA
P-AMINOBENZOIC ACID
P-ANIMOBENZOIC ACID
PARA AMINO BENZOIC ACID
PARAMINOL
RARECHEM AL BO 0238
VITAMIN BX
VITAMIN H1
4-Aminobenzoesαure
4-aminobenzoic
4-amino-benzoicaci
4-Aminobenzoic acid
p-amibenzoic acid
PABA,Vitamin Bx,Vitamin H1
PAPB
VitaMine H1
para-Aminobenzoic acid
potaba
rvpaba
Pabacyd
Pabagel
Pabanol
p-amino

MDL Number

MFCD00007894

Customs Code

29224995

FAQ

What is 4-Aminobenzoic acid (CAS: 150-13-0)?

4-Aminobenzoic acid is an organic compound with the chemical formula C7H7NO2. It is a white crystalline solid with a mild aromatic odor, commonly used as a precursor in the synthesis of various pharmaceuticals and dyes. It is soluble in water and polar organic solvents.

What are the main uses of 4-Aminobenzoic acid (CAS: 150-13-0)?

4-Aminobenzoic acid is primarily used in the pharmaceutical industry to produce drugs such as sulfasalazine and other sulfonamide antibiotics. It also finds applications in the synthesis of dyes, photographic chemicals, and as a food additive in some regions. In research, it serves as an intermediate for various organic reactions.

Is 4-Aminobenzoic acid (CAS: 150-13-0) safe?

4-Aminobenzoic acid is generally considered safe when handled properly. However, it can cause skin and eye irritation, and prolonged exposure may lead to adverse effects. Safety standards recommend using protective equipment and following proper disposal methods to ensure safe handling.

How should 4-Aminobenzoic acid (CAS: 150-13-0) be stored?

4-Aminobenzoic acid should be stored in a cool, dry, and well-ventilated area away from moisture and strong oxidizing agents. It is stable under normal storage conditions but should be kept in a tightly sealed container to prevent degradation and contamination.