5-oxopyrrolidine-2-carboxylic acid

Basic Information

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CAS Number

149-87-1

Molecular Formula

C5H7NO3

Molecular Weight

129.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

183-185 °C

Boiling Point

239.15°C (rough estimate)

Water Solubility

5.67 g/100 mL (20 ºC)

Flash Point

227.8 °C

Solubility

52g/l

Refractive Index

1.4220 (estimate)

SMILES

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C1CC(=O)NC1C(=O)O

InChI

InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)

InChIKey

ODHCTXKNWHHXJC-UHFFFAOYSA-N

LogP

-0.6504000000000001

Topological Polar Surface Area

66.39999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

154

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

PYROGLUTAMIC ACID, DL-
SY002490
6VT1YZM21H
HY-W012738
MFCD00064322
Q27887010
2-Pyrrolidone-5-carboxylic acid
SR-01000830710-3
(+/-)-pyroglutamic acid
NSC40887
(+/-)-2-pyrrolidone-5-carboxylic acid
PB42767
DTXSID80859174
dl-pyrrolidonecarboxylic acid
5-oxo-pyrrolidine-2-carboxylic acid
UNII-6VT1YZM21H
MLS001304098
PROLINE, 5-OXO-, DL-
FT-0605097
NS00085313
DL-Pidolic acid
G0061
D77751
149-87-1
SCHEMBL15791
HMS2269D08
DL-Proline, 5-oxo-
16891-48-8
5-Oxo-DL-proline
5-Oxoproline #
NSC 40887

MDL Number

MFCD00064322

Customs Code

29337900

FAQ

What is 5-oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1)?

5-Oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1) is a cyclic organic compound featuring a pyrrolidine ring with an oxo group at the 5-position and a carboxylic acid group at the 2-position. Its chemical formula is C5H9NO3, and it is commonly used as an intermediate in pharmaceutical and chemical synthesis. The compound is known for its stability and reactivity in various reactions, making it valuable in research applications.

What are the main uses of 5-oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1)?

5-Oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1) is primarily utilized in pharmaceutical research for synthesizing drugs and bioactive molecules. It also serves as a key intermediate in organic chemistry for creating complex compounds. Additionally, it finds applications in industrial chemical processes and academic studies due to its versatile functional groups and reactivity.

Is 5-oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1) safe?

5-Oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1) is generally considered safe when handled properly, but it may pose risks if inhaled, ingested, or exposed to skin. Safety data sheets recommend using appropriate protective equipment, such as gloves and goggles, and working in well-ventilated areas. It is classified as a chemical intermediate, so safety standards depend on its specific application and exposure conditions.

How should 5-oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1) be stored?

5-Oxopyrrolidine-2-carboxylic acid (CAS: 149-87-1) should be stored in a sealed, airtight container in a cool, dry place, away from light. It is stable under these conditions but may degrade if exposed to moisture or high temperatures. Proper storage ensures its chemical integrity and minimizes potential hazards during handling or use.