Squalamine | CAS No. 148717-90-2

Squalamine

Basic Information

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CAS Number

148717-90-2

Molecular Formula

C34H65N3O5S

Molecular Weight

627.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

SMILES

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CC(C)C(CCC(C)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)NCCCNCCCCN)C)O)C)OS(=O)(=O)O

InChI

InChI=1S/C34H65N3O5S/c1-23(2)31(42-43(39,40)41)12-9-24(3)27-10-11-28-32-29(14-16-34(27,28)5)33(4)15-13-26(21-25(33)22-30(32)38)37-20-8-19-36-18-7-6-17-35/h23-32,36-38H,6-22,35H2,1-5H3,(H,39,40,41)/t24-,25-,26+,27-,28+,29+,30-,31-,32+,33+,34-/m1/s1

InChIKey

UIRKNQLZZXALBI-MSVGPLKSSA-N

LogP

5.553200000000006

Topological Polar Surface Area

133.91 Å²

Hydrogen Bond Donor/Acceptor

6 / 8

Complexity

976

Synonyms & References

English

MSI-1256F (squalamine lactate)
Cholestane-7,24-diol, 3-((3-(4-(aminobutyl)amino)propyl)amio)-, 24-(hydrogen sulfate), (3beta,5alpha,7alpha,24R)-
F85142
HY-16468
SQUALAMINE [MI]
3-((3-(4-(Aminobutyl)amino)propyl)amio)cholestane-7,24-diol 24-(hydrogen sulfate), (3beta,5alpha,7alpha,24R)-
3beta-N-1-(N-[3-(4-aminobutyl)]- 1,3-diaminopropane)-7alpha,24R-dihydroxy-5alpha-cholestane 24-sulfate
(3beta,5alpha,7alpha,24R)-3-((3-(4-(Aminobutyl)amino)propyl)amio)cholestane-7,24-diol 24-(hydrogen sulfate)
SCHEMBL12836
Squalamine
CHEMBL444929
MS-30835
DTXSID40869971
DB06461
NS00071902
UNII-F8PO54Z4V7
MSI-1256
F8PO54Z4V7
3beta-N-1-(N-(3-(4-Aminobutyl))-1,3-diaminopropane)-7alpha,24-dihydroxy-5alpha-cholestane 24-sulfate
CHEBI:80765
[(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate
AKOS030526099
Squalamine [INN]
7alpha-Hydroxy, 3beta-spermidine
GTPL10861
Q15427852
148717-90-2
SQUALAMINE [WHO-DD]
LMST05050024
UIRKNQLZZXALBI-MSVGPLKSSA-N
Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)-

MDL Number

MFCD15146903

FAQ

What is Squalamine (CAS: 148717-90-2)?

Squalamine is a naturally occurring cationic peptide found in the liver of the dogfish shark. It is characterized by its ability to disrupt cell membranes and has been studied for its potential antimicrobial and anti-inflammatory properties.

What are the main uses of Squalamine (CAS: 148717-90-2)?

Squalamine has been investigated for its potential uses in pharmaceuticals, particularly as an antimicrobial agent against both Gram-positive and Gram-negative bacteria. It is also studied in the treatment of skin conditions and as an antiviral agent.

Is Squalamine (CAS: 148717-90-2) safe?

Squalamine generally appears to be safe for use in vitro and in animal models, but its safety in humans requires further clinical trials. It is important to follow all safety guidelines and precautions when handling the compound.

How should Squalamine (CAS: 148717-90-2) be stored?

Squalamine should be stored in a cool, dry place away from direct sunlight and heat. It should be kept in a tightly sealed container and away from moisture to prevent degradation. Storage at temperatures below 25°C is recommended to maintain its efficacy and stability.