4-(Benzyloxy)benzoic acid

Basic Information

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CAS Number

1486-51-7

Molecular Formula

C14H12O3

Molecular Weight

228.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

189.0 to 193.0 deg-C

Boiling Point

396.3°Cat760mmHg

Flash Point

152.3°C

SMILES

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C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=O)O

InChI

InChI=1S/C14H12O3/c15-14(16)12-6-8-13(9-7-12)17-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,15,16)

InChIKey

AQSCHALQLXXKKC-UHFFFAOYSA-N

LogP

2.963800000000001

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

238

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

Brl 14280
Z56869319
SCHEMBL228477
4-benzyloxy benzoic acid
4-Carboxyphenoxy phenyl methane
AKOS000109246
CS-W005179
p-(benzyloxy)benzoicacid
F3146-0159
4-Benzyloxybenzoic acid, 99%
4-Benzyloxybenzoic acid
BRD-K00030946-001-01-7
NSC-16633
SY004155
p-(Benzyloxy)benzoic acid
EINECS 216-066-0
NSC 16633
1486-51-7
4 - Carboxyphenoxy - phenyl methane
BRL-14280
BB 0245700
FT-0617664
4-(benzyloxy)benzoic acid
BDBM50496605
CK2186
p-benzyloxybenzoic acid
MS-1799
Q27449797
4-benzyloxybenzoate
BCP24385
CHEMBL3134411

MDL Number

MFCD00016527

Customs Code

2918990090

FAQ

What are the physical and chemical properties of 4-(Benzyloxy)benzoic acid (CAS: 1486-51-7)?

4-(Benzyloxy)benzoic acid is a white crystalline solid with a molecular weight of approximately 248.23 g/mol. It has a pKa of around 4.2. This compound is only slightly soluble in water but soluble in most organic solvents. It is moderately reactive towards bases and can undergo esterification reactions.

How is 4-(Benzyloxy)benzoic acid (CAS: 1486-51-7) typically synthesized?

4-(Benzyloxy)benzoic acid is typically synthesized by reacting benzoic acid with benzylic alcohol in the presence of a dehydrating agent like phosphorus pentoxide (P2O5) or thionyl chloride (SOCl2). The reaction is usually carried out under reflux conditions to ensure complete conversion and high yield.

What industries use 4-(Benzyloxy)benzoic acid (CAS: 1486-51-7)?

4-(Benzyloxy)benzoic acid is widely used in the pharmaceutical industry for the synthesis of intermediate compounds, as well as in the production of some active pharmaceutical ingredients. It also finds applications in the polymer industry for modifying the properties of plastics and in the chemical sensors industry for detecting specific analytes.

What precautions should be taken when handling 4-(Benzyloxy)benzoic acid (CAS: 1486-51-7)?

When handling 4-(Benzyloxy)benzoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up carefully using appropriate absorbent materials and following standard safety protocols. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.