Sitagliptin Impurity 1 | CAS No. 1485732-85-1

Sitagliptin Impurity 1

Basic Information

CAS Number

1485732-85-1

Molecular Formula

C8H12ClF3N6O

Molecular Weight

300.67 g/mol

AD

Basic Physical Properties

Cl.FC(C1=NN=C2CN(CC(NN)=O)CCN21)(F)F

InChI

1S/C8H11F3N6O.ClH/c9-8(10,11)7-15-14-5-3-16(1-2-17(5)7)4-6(18)13-12;/h1-4,12H2,(H,13,18);1H

InChIKey

MICCIYLDKANHAC-UHFFFAOYSA-N

LogP

-0.47580000000000044

Topological Polar Surface Area

89.07000000000002 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

324

Synonyms & References

English

  • Sitagliptin Impurity 1
  • 2-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)acetohydrazide

FAQ

What regulatory guidelines apply to Sitagliptin Impurity 1 (CAS: 1485732-85-1)?

Sitagliptin Impurity 1 (CAS: 1485732-85-1) must comply with GHS classification for hazardous chemicals, REACH regulations for substance registration, evaluation, and authorization in the European Union, FDA guidelines for drug development and production, and EPA regulations for environmental protection. Proper documentation and reporting are required to ensure compliance with these regulatory standards.

Are there alternatives to Sitagliptin Impurity 1 (CAS: 1485732-85-1) in synthesis?

Alternatives to Sitagliptin Impurity 1 (CAS: 1485732-85-1) in synthesis include using isomers or analogs of the compound. Common alternatives may involve substituting reagents or adjusting reaction conditions to achieve a similar or improved product. It is crucial to evaluate the safety and efficacy of these alternatives in the context of the overall synthesis process.

What is the market or research trend for Sitagliptin Impurity 1 (CAS: 1485732-85-1)?

The market trend for Sitagliptin Impurity 1 (CAS: 1485732-85-1) reflects a focus on regulatory compliance and safety in drug development. Research trends are centered on understanding the impact of impurities on drug efficacy and safety. Emerging research is also exploring the potential of these impurities in other applications or as new pharmaceutical candidates.

How should waste containing Sitagliptin Impurity 1 (CAS: 1485732-85-1) be handled?

Waste containing Sitagliptin Impurity 1 (CAS: 1485732-85-1) should be collected in appropriate containers and stored separately from other waste materials. Incineration or professional waste disposal services should be utilized to ensure safe and effective elimination of the waste. Environmental protection measures, including proper labeling and documentation, are essential to prevent contamination and ensure compliance with regulatory requirements.

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