N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine | CAS No. 148515-86-0

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine

Basic Information

CAS Number

148515-86-0

Molecular Formula

C43H39NO8

Molecular Weight

697.78 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (3.5E-6 g/L) (25 ºC),

COc1ccc(c(c1)OC(=O)OCC1c2ccccc2c2c1cccc2)CN([C@H](C(=O)O)C(C)C)C(=O)OCC1c2ccccc2c2c1cccc2

InChI

InChI=1S/C43H39NO8/c1-26(2)40(41(45)46)44(42(47)50-24-37-33-16-8-4-12-29(33)30-13-5-9-17-34(30)37)23-27-20-21-28(49-3)22-39(27)52-43(48)51-25-38-35-18-10-6-14-31(35)32-15-7-11-19-36(32)38/h4-22,26,37-38,40H,23-25H2,1-3H3,(H,45,46)/t40-/m0/s1

InChIKey

SEBWBBFTTQDBSZ-FAIXQHPJSA-N

LogP

8.883400000000004

Topological Polar Surface Area

111.60000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 9

Complexity

1180

Synonyms & References

English

  • FMOC-(FMOCHMB)VAL-OH
  • FMOC-[FMOC-HMB]-VAL-OH
  • FMOC-(FMOC-O-PMEOBZL)VAL-OH
  • FMOC-[2-N-ALPHA-FMOC-OXY-4-METHOXYBENZYL]-L-VALINE
  • N-ALPHA-FMOC-N-ALPHA-(2-FMOC-OXY-4-METHOXYBENZYL)-VALINE
  • N-ALPHA-FMOC-N-ALPHA-(2-FMOC-OXY-4-METHOXYBENZYL)-L-VALINE
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl ((9H-Fluoren-9-yl)MethOxy]Carbonyl Hmb)-Val-OH
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-4-methoxyphenyl]methyl]-L-valine
  • (S)-2-((((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonyl)(9H-fluoren-9-yl)methoxy)carbonyloxy)-4-methoxybenzyl)amino)-3-methylbutanoic acid

MDL Number

MFCD00278816

FAQ

What are the physical and chemical properties of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine (CAS: 148515-86-0)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine is a crystalline compound with a molecular weight of approximately 913.5 g/mol. It has a moderate solubility in organic solvents like dichloromethane and acetone. The compound is chemically stable under normal conditions but reacts with strong bases and acids. It is used in various applications requiring high purity and stability.

How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine (CAS: 148515-86-0) typically synthesized?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine is synthesized using a multi-step process involving amidation, esterification, and coupling reactions. Commonly, this compound is produced using protected amino acids and appropriate protecting groups. The synthesis typically involves high yields and good selectivity.

What industries use N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine (CAS: 148515-86-0)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine is primarily used in the pharmaceutical industry for synthesizing complex organic molecules and in the research and development of new drug candidates. It is also utilized in the polymer industry for developing advanced materials with specific properties.

What precautions should be taken when handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine (CAS: 148515-86-0)?

Proper handling of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}-4-methoxybenzyl)-L-valine requires the use of personal protective equipment (PPE), including gloves and goggles. It should be handled in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

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