2-(2-Piperidinyl)ethanol

Basic Information

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CAS Number

1484-84-0

Molecular Formula

C7H15NO

Molecular Weight

129.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

38-40 °C

Boiling Point

234 °C

Refractive Index

1.4749 (estimate)

SMILES

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C1CCNC(C1)CCO

InChI

InChI=1S/C7H15NO/c9-6-4-7-3-1-2-5-8-7/h7-9H,1-6H2

InChIKey

PTHDBHDZSMGHKF-UHFFFAOYSA-N

LogP

0.5108999999999997

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

75.3

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

Hazard Class

Class 8 Class 8

Synonyms & References

English

2-Piperidine ethanol
2-Ethanolpiperidine, 95per cent
FT-0608479
2-PIPERIDINEETHANOL
2-piperidinethanol
NSC9261
SY111895
UNII-EHY6X8X6JQ
PTHDBHDZSMGHKF-UHFFFAOYSA-
(R)-2-(2-Piperidyl)ethanol
2-(HYDROXYETHYL)PIPERIDINE
2-(2-Piperidinyl)ethanol #
AI3-36432
AM20080368
W-109672
J133C
2-(2-piperidyl)ethan-1-ol
(S)-2-(2-Piperidyl)ethanol
Tox21_301688
EINECS 216-059-2
2-(Piperidin-2-Yl)Ethan-1-Ol
(S)-2-(Piperidin-2-yl)ethanol;2-[(2S)-2-piperidyl]ethanol
CS-W001979
SB42990
2(R/S)-(2-Hydroxyethyl)piperidine
AKOS016050704
AKOS000120680
EN300-21001
SB42942
Q18611680
NCGC00256091-01

MDL Number

MFCD00005989

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-(2-Piperidinyl)ethanol (CAS: 1484-84-0)?

2-(2-Piperidinyl)ethanol (CAS: 1484-84-0) is a colorless or light yellow liquid with a molecular weight of approximately 141.25 g/mol. It has a piperidine-like odor and is soluble in water and ethanol. The compound is moderately reactive towards acids and bases. It has a low melting point and is miscible with polar organic solvents.

How is 2-(2-Piperidinyl)ethanol (CAS: 1484-84-0) typically synthesized?

2-(2-Piperidinyl)ethanol is typically synthesized by the reaction of 2-piperidinemethanol with ethanol. The reaction is usually catalyzed by a strong acid like hydrochloric acid, and the desired product can be isolated by column chromatography. The yield is generally around 70-80%, and the method involves mild conditions to ensure high selectivity.

What industries use 2-(2-Piperidinyl)ethanol (CAS: 1484-84-0)?

2-(2-Piperidinyl)ethanol (CAS: 1484-84-0) is used in various industries, particularly in the pharmaceutical sector for its role as a precursor in the synthesis of certain drugs. It is also utilized in polymer manufacturing as a surfactant and in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2-(2-Piperidinyl)ethanol (CAS: 1484-84-0)?

When handling 2-(2-Piperidinyl)ethanol (CAS: 1484-84-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation of the vapor. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for detailed spill handling procedures.