Pexiganan | CAS No. 147664-63-9

Pexiganan

Basic Information

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CAS Number

147664-63-9

Molecular Formula

C122H210N32O22

Molecular Weight

2477.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

2261.8°Cat760mmHg

Density

1.18

Flash Point

1321.7°C

Refractive Index

1.552

SMILES

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CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=CC=C2)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N)NC(=O)CN

InChI

InChI=1S/C122H210N32O22/c1-13-77(9)102(152-98(155)71-132)120(174)135-73-100(157)139-86(50-26-35-59-125)110(164)150-96(69-82-44-20-16-21-45-82)118(172)148-93(66-74(3)4)116(170)145-90(54-30-39-63-129)113(167)142-87(51-27-36-60-126)109(163)137-79(11)105(159)141-88(52-28-37-61-127)112(166)143-91(55-31-40-64-130)114(168)149-95(68-81-42-18-15-19-43-81)107(161)134-72-99(156)138-85(49-25-34-58-124)108(162)136-80(12)106(160)147-97(70-83-46-22-17-23-47-83)119(173)153-101(76(7)8)121(175)146-92(56-32-41-65-131)115(169)154-103(78(10)14-2)122(176)151-94(67-75(5)6)117(171)144-89(53-29-38-62-128)111(165)140-84(104(133)158)48-24-33-57-123/h15-23,42-47,74-80,84-97,101-103H,13-14,24-41,48-73,123-132H2,1-12H3,(H2,133,158)(H,134,161)(H,135,174)(H,136,162)(H,137,163)(H,138,156)(H,139,157)(H,140,165)(H,141,159)(H,142,167)(H,143,166)(H,144,171)(H,145,170)(H,146,175)(H,147,160)(H,148,172)(H,149,168)(H,150,164)(H,151,176)(H,152,155)(H,153,173)(H,154,169)/t77-,78-,79-,80-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,101-,102-,103-/m0/s1

InChIKey

KGZGFSNZWHMDGZ-KAYYGGFYSA-N

LogP

12.45450

Topological Polar Surface Area

914.3899999999999 Å²

Hydrogen Bond Donor/Acceptor

43 / 54

Complexity

4940

Synonyms & References

English

Pexiganan
L-Lysinamide, glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanylglycyl-L-lysyl-L-alanyl-L-phenylaalanyl-L-valyl-L-lysyl-L-isoleucyl-L-leucyl-L-lysyl-
147664-63-9
Pexiganan [INN]
GLY-ILE-GLY-LYS-PHE-LEU-LYS-LYS-ALA-LYS-LYS-PHE-GLY-LYS-ALA-PHE-VAL-LYS-ILE-LEU-LYS-LYS-NH2
CHEMBL1275802
7-L-LYSINE-8-L-LYSINE-10-L-LYSINE-18-L-LYSINE-19-DE-L-GLUTAMIC ACID-21-L-LEUCINE-23-L-LYSINAMIDE MAGAININ I
Magainin I, 7-L-lysine-8-L-lysine-10-L-lysine-18-L-lysine-19-de-L-glutamic acid-21-L-leucine-23-L-lysinamide
PEXIGANAN [MI]
SCHEMBL476400
EX-A7466
TVF29Q70Q1
Glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanylglycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-lysyl-L-isoleucyl-L-leucyl-L-lysyl-L-lysinamide
UNII-TVF29Q70Q1
L-Lysinamide,glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanylglycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-lysyl-L-isoleucyl-L-leucyl-L-lysyl-
L-Lysinamide,glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl...
L-Lysinamide,glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanyl
L-Lysinamide,glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanylglycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-lysyl-L-isoleucyl-L-leucyl
Pexiganan Acetate
L-Lysinamide, glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl

MDL Number

MFCD07772290

FAQ

What is Pexiganan (CAS: 147664-63-9)?

Pexiganan (CAS: 147664-63-9) is a cyclic tetrapeptide with antibacterial and antifungal properties. It is derived from the skin secretion of the newt Echinosternus trivittatus and is used in the development of topical antibiotics and antimicrobial agents.

What are the main uses of Pexiganan (CAS: 147664-63-9)?

Pexiganan (CAS: 147664-63-9) is primarily used in the pharmaceutical industry for developing topical antibiotics and antimicrobial agents. It is also applied in research for studying natural compounds with potential therapeutic applications.

Is Pexiganan (CAS: 147664-63-9) safe?

Pexiganan (CAS: 147664-63-9) is generally considered safe when used as directed. However, it is important to follow all safety guidelines, including wearing gloves and protective clothing during handling. Allergic reactions may occur, so it is advisable to perform a patch test before use.

How should Pexiganan (CAS: 147664-63-9) be stored?

Pexiganan (CAS: 147664-63-9) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to protect it from moisture and contamination. Optimal storage conditions are between 15-25°C (59-77°F).