N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide | CAS No. 1474110-21-8

N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide

Basic Information

CAS Number

1474110-21-8

Molecular Formula

C25H35NO5S

Molecular Weight

461.62 g/mol

AD

Basic Physical Properties

CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c2ccc(c(c2)CO)OCC3CCOCC3

InChI

InChI=1S/C25H35NO5S/c1-4-20-5-7-23(8-6-20)26(16-19(2)3)32(28,29)24-9-10-25(22(15-24)17-27)31-18-21-11-13-30-14-12-21/h5-10,15,19,21,27H,4,11-14,16-18H2,1-3H3

InChIKey

LZLBRISQTJVZNP-UHFFFAOYSA-N

LogP

4.398000000000004

Topological Polar Surface Area

76.07000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Synonyms & References

English

  • N-(4-ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-((tetrahydro-2H-pyran-4-yl)methoxy)benzenesulfonamide
  • Benzenesulfonamide, N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-[(tetrahydro-2H-pyran-4-yl)methoxy]-
  • GSK2981278
  • N-(4-Ethyl-phenyl)-3-hydroxymethyl-N-isobutyl-4-(tetrahydro-pyran-4-ylmethoxy)-benzenesulfonamide

MDL Number

MFCD29059455

FAQ

What are the physical and chemical properties of N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8)?

N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8) is a crystalline compound with a molecular weight of approximately 567.8 g/mol. It has poor water solubility and moderate solubility in organic solvents. The compound is moderately reactive due to the presence of hydroxyl and sulfonamide groups. It can be used as a precursor in various chemical syntheses, and its reactivity makes it suitable for forming covalent bonds in specific reactions.

How is N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8) typically synthesized?

N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8) is typically synthesized using a multi-step process involving condensation reactions, alkylation, and sulfonation. The synthesis requires the use of appropriate catalysts and solvents to ensure high yield and selectivity. Commonly used solvents include dichloromethane and tetrahydrofuran, while catalysts like sulfuric acid are often employed.

What industries use N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8)?

N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8) is used in the pharmaceutical industry as a precursor for drug development. It is also utilized in the polymer industry for enhancing material properties. Additionally, it finds applications in the sensor and semiconductor industries for specific chemical sensing and electronic device fabrication.

What precautions should be taken when handling N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8)?

When handling N-(4-Ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)benzenesulfonamide (CAS: 1474110-21-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area, ideally within a fume hood, to minimize exposure. In case of a spill, immediately clean up using appropriate absorbent materials, ensuring proper disposal according to local regulations. Always refer to the safety data sheet (SDS) for specific handling and disposal instructions.

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