({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid | CAS No. 147127-20-6

({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid

Basic Information

CAS Number

147127-20-6

Molecular Formula

C9H14N5O4P

Molecular Weight

287.22 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

276-280 ºC

Boiling Point

616.1 °C at 760 mmHg

Density

1.79

Water Solubility

13.4 mg/mL (25 ºC)

Flash Point

326.4 °C

Specific Rotation

D +21° (c = 1 in 0.1M HCl)

CC(CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O

InChI

InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1

InChIKey

SGOIRFVFHAKUTI-ZCFIWIBFSA-N

LogP

-0.051200000000000134

Topological Polar Surface Area

136.38000000000002 Ų

Hydrogen Bond Donor/Acceptor

4 / 9

Complexity

354

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H332 Harmful if inhaled
Acute toxicity, inhalation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • DTXCID7020132
  • (((1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonic acid
  • tenofovir (anh.)
  • (R)-9-(Phosphonomethoxypropyl)adenine
  • Q155954
  • Tenofovir (Viread)
  • NCGC00167535-16
  • anh. tenofovir
  • Z1546616194
  • [(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methylphosphonic acid
  • [2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY]METHYLPHOSPHONIC ACID
  • CS-1609
  • Tenofovir [USAN:INN:BAN]
  • C17407
  • A808613
  • SCHEMBL39724
  • UNII-99YXE507IL
  • T3006
  • ((((2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid
  • Tenofovir gel (GS-1278)
  • PMP-A
  • PMPA-(R)
  • D,L-Tenofovir
  • AB01274787-01
  • Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)
  • Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, monohydrate, (R)-
  • Q-201787
  • tenofovir (anhydrous)
  • CHEMBL483
  • TFO
  • KS-5021

MDL Number

MFCD00943794

Customs Code

2933990090

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