Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate | CAS No. 147118-35-2
Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate
Basic Information
CAS Number
147118-35-2
Molecular Formula
C31H39O4PSi
Molecular Weight
534.71 g/mol
AD
Chemical Classification
Basic Physical Properties
Physical State
Powder
Melting Point
98-100°C
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H332
Harmful if inhaled
Acute toxicity, inhalation
Acute toxicity, inhalation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- J-521706
- C31H39O4PSi
- Methyl (R)-3-((tert-butyldimethylsilyl)oxy)-5-oxo-6-(triphenyl-l5-phosphanylidene)hexanoate
- Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate
- (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate methyl ester
- Methyl (3R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-6-(triphenylphosphoranylidene)hexanoate
- Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidene hexanoate
- methyl (3R)-3-[(tert-butyldimethylsilyl)oxy]-5-oxo-6-(triphenyl--phosphanylidene)hexanoate
- Methyl(3R)-3-(Tert-Butyldimethylsilanyloxy)-5-Oxo-6-(Triphenylphosphanylidene)Hexanoate
- DTXSID701114586
- methyl (3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-oxo-6-(triphenyl-lambda5-phosphanylidene)hexanoate
- 147118-35-2
- AM84433
- SCHEMBL2345036
- MFCD09753068
- BCP10932
- A24818
- AS-15931
- CS-0148491
- methyl (3r)-3-(dimethyl(2-methyl-2-propanyl)silyloxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate
- Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate
- (R)-Methyl 3-((tert-butyldimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate
- Hexanoic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-6-(triphenylphosphoranylidene)-, methyl ester, (3R)-
- AKOS015896175
- Methyl (3R)-3-[tert-Butyl(dimethyl)silyl]oxy-5-oxo-6-(triphenylphosphanylidene)hexanoate
- J-6: Methyl(3R)-3-(tert-butyldimethylsilyloxy)-5-
- Rosuvastatin J-6
- (R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxo]-5-oxo-6-(triphenylphosphoranylidene)-methyl hexanoate
- B-8
- METHYL (3R)-3-(TERT-BUTYLDIMETHYL SILYLOXY)-5-OXO-6-TRIPHENYL PHOSPHORANYLIDENE HEXANOATE (J6)
- methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate
MDL Number
MFCD09753068
FAQ
What are the physical and chemical properties of Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate (CAS: 147118-35-2)?
Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate is a crystalline compound with a molecular weight of approximately 612.75 g/mol. It has limited solubility in water but is soluble in organic solvents like chloroform and ethyl acetate. The compound exhibits high reactivity towards nucleophiles and is known for its stability under anhydrous conditions. It is insoluble in alcohols and ethers. Due to its complex structure, it is typically synthesized using organosilicon and organophosphorus reagents.
How is Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate (CAS: 147118-35-2) typically synthesized?
Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate is synthesized through a multi-step process involving the use of silyl and phosphorus reagents. A typical synthesis involves the reaction of a silyl ether with an appropriate phosphorus reagent under anhydrous conditions. The yield is generally high, and the reaction is carried out in an inert atmosphere to prevent unwanted side reactions.
What industries use Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate (CAS: 147118-35-2)?
Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate is primarily used in the pharmaceutical and fine chemical industries. It serves as a key intermediate in the synthesis of various organic compounds and is also utilized in the development of new materials and sensors. Its complex structure makes it valuable for research in organophosphorus chemistry and organosilicon chemistry.
What precautions should be taken when handling Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate (CAS: 147118-35-2)?
When handling Methyl (3R)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-oxo-6-(triphenylphosphoranylidene)hexanoate, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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