N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine | CAS No. 146982-27-6

N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

Basic Information

CAS Number

146982-27-6

Molecular Formula

C25H28N2O6

Molecular Weight

452.51 g/mol

AD

Basic Physical Properties

Boiling Point

689.7°C at 760 mmHg

Density

1.2370

C=CCOC(=O)NCCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1

InChIKey

OJBNDXHENJDCBA-QFIPXVFZSA-N

LogP

4.060800000000003

Topological Polar Surface Area

113.96000000000002 Ų

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

662

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H332 Harmful if inhaled
Acute toxicity, inhalation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-(prop-2-enoxycarbonylamino)hexanoic acid
  • 146982-27-6
  • DTXSID60456004
  • N2-Fmoc-N6-[(allyloxy)carbonyl]-L-lysine
  • J-008294
  • Fmoc-L-Lys(Alloc)-OH
  • OJBNDXHENJDCBA-QFIPXVFZSA-N
  • N6-[(Allyloxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
  • (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-(allyloxycarbonylamino)hexanoic acid
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6-{[(prop-2-en-1-yloxy)carbonyl]amino}hexanoic acid
  • FMOC-LYS(ALOC)-OH
  • Nalpha-Fmoc-Nepsilon-Alloc-L-lysine
  • MFCD00190872
  • AMY22601
  • M06250
  • Fmoc-Lys(Alloc)-OH
  • Fmoc-Lys(Alloc)
  • F10643
  • EN300-1663059
  • HY-W010862
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-ALLYLOXYCARBONYL-L-LYSINE
  • Fmoc-Lys(Alloc)-OH, >=95.0% (HPLC)
  • (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-6-[[oxo(prop-2-enoxy)methyl]amino]hexanoic acid
  • N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(2-propen-1-yloxy)carbonyl]-L-lysine
  • J-014092
  • N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((allyloxy)carbonyl)-L-lysine
  • CS-W011578
  • AKOS015896285
  • DS-13791
  • A808576
  • (S)-2-((((9H-fFuoren-9-yl)methoxy)carbonyl)amino)-6-(((allyloxy)carbonyl)amino)hexanoic acid

MDL Number

MFCD00190872

Customs Code

2924299090

FAQ

What are the physical and chemical properties of N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6)?

N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6) is a crystalline compound with a molecular weight of approximately 598.6 g/mol. It is poorly soluble in water but soluble in organic solvents. This compound is reactive towards nucleophiles and can participate in various chemical reactions, such as esterification and amidation.

How is N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6) typically synthesized?

N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6) can be synthesized through a multi-step process involving coupling reactions, carboxylic acid activation, and derivatization. Commonly, this involves the use of activated carboxylic acids, such as fluorenylmethyl chloroformate, and protecting groups like allyl chlorides. The final product is obtained with good yield and selectivity under mild conditions.

What industries use N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6)?

N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6) is primarily used in the pharmaceutical and polymer industries for the synthesis of drug intermediates and as a building block for polymers. It is also utilized in the development of sensors and semiconductors where its unique chemical structure is advantageous.

What precautions should be taken when handling N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6)?

When handling N~6~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (CAS: 146982-27-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate chemicals and procedures, and the material safety data sheet (MSDS) should be consulted for detailed safety information.

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