5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one

Basic Information

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CAS Number

146939-27-7

Molecular Formula

C21H21ClN4OS

Molecular Weight

412.95 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

218.0 to 224.0 deg-C

Boiling Point

554.8±50.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Flash Point

289.3±30.1 °C

Refractive Index

1.681

Vapor Pressure

0.0±1.5 mmHg at 25°C

SMILES

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Clc1cc2NC(=O)Cc2cc1CCN3CCN(CC3)c4nsc5ccccc45

InChI

InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)

InChIKey

MVWVFYHBGMAFLY-UHFFFAOYSA-N

LogP

3.809000000000003

Topological Polar Surface Area

48.470000000000006 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

573

Safety Information

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GHS Hazard Pictograms

H336

Hazard Statement

H336 May cause drowsiness or dizziness
Specific target organ toxicity, single exposure; Narcotic effects

Synonyms & References

English

Ziprasidone
-(2-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one
5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
ZIPRASIDON
Ziprasidone solution
CP 88059
CP-88059
Geodon
UNII-6UKA5VEJ6X
Zeldox
ziprasidona
Ziprasidone [INN:BAN]
ziprasidonum
ziprazidone
5-(2-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one
ZIPRASIDONE-D8
Ziprasidone HBr
CP-88059：CP-88059-1
Hydrochloric acid(base)
ZIPRASIDONE: ZIPRASIDONE HYDROCHLORIDE MONOHYDRATE
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
Ziprasidone hydrochloride
Ziprasidone mesylate trihydrate
6UKA5VEJ6X
C21H21ClN4OS
DSSTox_CID_3753
DSSTox_RID_77186
DSSTox_GSID_23753
2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-
5-(2-(4-(benzo[d]isothiazol-3-yl)

MDL Number

MFCD00866661

Customs Code

29211980

FAQ

What is 5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one (CAS: 146939-27-7)?

5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one is a complex organic compound. It has a molecular formula of C22H23ClN5S and exhibits characteristics of a chlorinated indole derivative with a benzothiazole and piperazine moiety. This compound is primarily used in pharmaceutical research and development for its potential therapeutic properties.

What are the main uses of 5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one (CAS: 146939-27-7)?

Main uses of 5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one include its application in pharmaceutical research for developing new drugs. It serves as a starting material for synthesizing derivatives with potential analgesic, antipsychotic, and anti-inflammatory properties.

Is 5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one (CAS: 146939-27-7) safe?

5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one is generally safe for laboratory use under controlled conditions. However, appropriate safety measures such as wearing gloves, safety goggles, and a lab coat are recommended. Handling should be done in a well-ventilated area to avoid inhalation of dust or vapors.

How should 5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one (CAS: 146939-27-7) be stored?

5-{2-[4-(1,2-Benzothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. For safety, store the compound in a secure, labeled container and ensure it is inaccessible to unauthorized personnel.