4-Amino-2,2,6,6-tetramethyl-1-piperidinol

Basic Information

View in Editor

CAS Number

14691-88-4

Molecular Formula

C9H20N2O

Molecular Weight

171.26 g/mol

EINECS

238-738-2

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

37-39°C

Boiling Point

98 °C / 4mmHg

Density

0.9977 (rough estimate)

Flash Point

39 °C

Refractive Index

1.4480 (estimate)

SMILES

View in Editor

NC1CC(C)(C)N(C(C1)(C)C)[O]

InChI

InChI=1S/C9H20N2O/c1-8(2)5-7(10)6-9(3,4)11(8)12/h7,12H,5-6,10H2,1-4H3

InChIKey

AYSOUYKQIUYGFR-UHFFFAOYSA-N

LogP

1.3121999999999998

Topological Polar Surface Area

49.16 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

159

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

4-amino-2,2,6,6-tetramethyl-1-piperidinylox
tempamine
2,2,6,6-TETRAMETHYL-4-AMINO-1-PIPERIDINYLOXY
4-AMINO-1-OXY-2,2,6,6-TETRAMETHYLPIPERIDINE
4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINO-1-OXYL
4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY
4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINOXY FREE RADICAL
4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINYLOXY
4-Amino-2,2,6,6-tetramethylpiperidinooxy
4-AMINO-TEMPO
4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical
4-Amino-Tempo, Free Radical
1-Piperidinyloxy,4-amino-2,2,6,6-tetramethyl-
4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL FREE RADICAL [SPIN LABEL]
4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl
4-Amino-2,2,6,6-tetramethylpiperidino-1-oxyl
4-Amino-2,2,6,6-tetramethylpiperidinyloxy
4-Amino-2,2,6,6-tetramethylpiperidinooxy,free radical
4-Amino-TEMPO Free Radical (purified by sublimation)
Piperidinooxy,4-amino-2,2,6,6-tetramethyl- (8CI)
(2,2,6,6-Tetramethyl-1-oxy-4-piperidinyl)amine
2,2,6,6-Tetramethyl-1-oxy-4-aminopiperidine
2,2,6,6-Tetramethyl-4-amino-1-piperidinyloxy
2,2,6,6-Tetramethyl-4-aminopiperidine N-oxide
2,2,6,6-Tetramethyl-4-aminopiperidine-1-oxyl
4-Amino-1-oxyl-2,2,6,6-tetramethylpiperidine
4-Amino-2,2,6,6-tetramethyl-1-piperidinyloxy
4-Amino-2,2,6,6-tetramethyl-1-piperidinyloxyl
4-Amino-2,2,6,6-tetramethylpiperidin-1-oxyl
4-Amino-2,2,6,6-tetramethylpiperidine N-oxide
4-Amino-2,2,6,6-tetramethylpiperidine-1-nitroxide

MDL Number

MFCD00006479

EC Number

238-738-2

Customs Code

29333990

FAQ

What are the physical and chemical properties of 4-Amino-2,2,6,6-tetramethyl-1-piperidinol (CAS: 14691-88-4)?

4-Amino-2,2,6,6-tetramethyl-1-piperidinol is a crystalline compound with a molecular weight of approximately 232.32 g/mol. It has a high solubility in organic solvents such as methanol and ethanol, while being almost insoluble in water. Chemically, it is a powerful antioxidant and free radical scavenger, making it highly reactive with various free radicals in biological and chemical systems.

How is 4-Amino-2,2,6,6-tetramethyl-1-piperidinol (CAS: 14691-88-4) typically synthesized?

4-Amino-2,2,6,6-tetramethyl-1-piperidinol can be synthesized through the reduction of 4-nitro-2,2,6,6-tetramethyl-1-piperidone. The process typically involves the use of sodium borohydride as a reducing agent. The yield is generally around 70-80%, with high selectivity and good purity.

What industries use 4-Amino-2,2,6,6-tetramethyl-1-piperidinol (CAS: 14691-88-4)?

4-Amino-2,2,6,6-tetramethyl-1-piperidinol is widely used in the pharmaceutical industry as a precursor for antioxidants and as a stabilizer in cosmetics. It is also utilized in the polymer industry as a radical scavenger, in sensors for its redox properties, and in semiconductors for its stability in high-temperature environments.

What precautions should be taken when handling 4-Amino-2,2,6,6-tetramethyl-1-piperidinol (CAS: 14691-88-4)?

When handling 4-Amino-2,2,6,6-tetramethyl-1-piperidinol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.